Topics in Bacterial Pathogenesis – ZRG1 IDM-B 80
Scientific Review Officer
The Topics in Bacterial Pathogenesis Special Emphasis Panels [IDM- 80 and 81] reviews R21 and R03 applications that would otherwise be reviewed by either the Bacterial Pathogenesis (BACP) or Host Interactions with Bacterial Pathogens (HIBP) Study Sections.
It reviews applications addressing regulation and determinants of bacterial virulence and pathogenicity, bacterial factors that alter/affect host cells, and host-pathogen interactions. In vitro and in vivo animal model studies may be at the genetic, biochemical or cell biological level.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
Review Dates
Topics
- Genetic, biochemical and structural characterization of the regulation and determinants of virulence and pathogenicity, including: capsules, toxins, and supramolecular structures
- Role of bacterial behavior and developmental processes in the host pathogen interaction, including: biofilms, chemotaxis, sporulation, and stress responses
- Mechanisms of persistence and transmission
- Ecology of bacterial pathogens including the composition of the indigenous microbiota and its role in health and disease
- Animal models of infection with bacteria
- Molecular basis for bacteria-host interactions including: in vivo survival and growth, intracellular replication dissemination, intercellular spread
- Immune response of the host to bacteria, characterization of the role of immunomodulators and effector molecules in pathogenicity, manipulation and evasion of innate and adaptive immune responses
- Interplay between bacteria and host cell components and processes, subversion and manipulation of normal host cell processes
- Mechanisms of asymptomatic colonization and the balance between infection and disease, and commensalism and pathogenicity
- Animal models of infection and disease, including host genetic determinants of susceptibility and resistance and surrogate hosts
Overlaps with Closely Related Study Sections
There are shared interests with Prokaryotic Cell and Molecular Biology Study Section (PCMB) in the investigations of the process of bacterial infections. Grant applications that focus on the basic genetics, biochemistry and physiology of bacterial pathogens may be reviewed in PCMB. R21 and R03 applications that focus on the pathogenesis associated with bacterial infections may be reviewed in IDM (80) or IDM (81).
There are shared interests with Oral, Dental and Craniofacial Sciences Study Section (ODCS) in the investigations of the process of bacterial infections. Grant applications that focus on studies related to oral microbiology may be reviewed in ODCS. R21 and R03 applications that focus on general pathogenesis issues associated with bacterial infections may be reviewed in IDM (80) or IDM (81).
There are shared interests with Drug Discovery and Mechanisms of Antimicrobial Resistance (DDR) in the investigations of the process of bacterial infections. Grant applications that focus on antimicrobial resistance mechanisms and drug discovery studies for bacterial pathogens may be reviewed in DDR. R21 and R03 applications that focus on general pathogenesis issues associated with bacterial infections may be reviewed in IDM (80) or IDM (81).
There are shared interests with Clinical Research and Field Studies of Infectious Diseases (CRFS) in the investigations of the process of bacterial infections. Grant applications that focus on epidemiology, diagnostics, emergence, spread and control of bacterial pathogens in the context of human infections may be reviewed in CRFS. R21 and R03 applications that focus on general pathogenesis issues associated with bacterial infections may be reviewed in IDM (80) or IDM (81).
There are shared interests with Immunity and Host Defense Study Section (IHD) in the investigations of the process of bacterial infections. Grant applications that focus on the understanding of the innate and adaptive immune responses to infectious agents that include mechanisms of immune responses and animal models may be reviewed in IHD. R21 and R03 applications that focus on the bacterial pathogenesis process, including elements of host defense, may be reviewed in IDM (80) or IDM (81).
