Sepsis and injury studies reviewed by SAT often address the host response to such complex insults as trauma, severe infection, or surgical stress, with a general focus on metabolic, hormonal, cellular, or immune responses of the host to these various insults. SAT also reviews applications examining the basis of interventions including mechanisms of anesthesia/analgesia, wound repair, organ recovery, and cellular and immunological therapies. Topics related to anesthesiology and surgical critical care are comprehensively reviewed.

 

The List of Reviewers lists all present, whether permanent or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.

Review Dates

Membership Panel

The membership panel is a list of chartered members only.

Topics


  • Tissue, organ and systemic injury responses to surgery, trauma, burn, sepsis, hemorrhage, ischemia-reperfusion, or resuscitation, mechanisms of host response. including integrating pathways and signals
  • Modeling, pathogenesis and therapeutic interventions for shock and multiple organ failure, and for hypoxic or oxidative cell/tissue injury and stress-induced cellular turnover and repair
  • Skin and integument wound healing, including tissue/organ regeneration, and remodeling of damaged tissues, and novel therapeutic interventions for maintenance or restoration of tissue function.
  • Mechanisms of action and pharmacology of general and local anesthetics, and pain management, including general and local anesthesia, and anesthetic side effects
  • Surgical approaches to organ/tissue-specific disease, injury, or repair including minimally invasive approaches and transluminal surgery
  • Genetic and epigenetic determinants of response to injury or sepsis; and genetic, epigenetic, or pharmacologic approaches for treatment

Shared Interests and Overlaps

There are shared interests with Myocardial Ischemia and Metabolism (MIM) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on mechanisms of myocardial ischemia reperfusion injury may be assigned to MIM.

There are shared interests with Neural Oxidative Metabolism and Death Study Section (NOMD) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on molecular mechanisms underlying neural injury associated with ischemia, reperfusion injury, and traumatic brain injury may be assigned to NOMD.

There are shared interests with Digestive, Kidney and Urological Systems IRG (DKUS) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on liver ischemia-reperfusion injury and application of transplantation to the therapy of liver diseases may be assigned to DKUS.

There are shared interests with Clinical and Integrative Cardiovascular Sciences Study Section (CICS) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on patients oriented research on cardiovascular injury and repair, and myocardial ischemia/reperfusion injury may be assigned to CICS .

There are shared interests with Clinical, Integrative and Molecular Gastroenterology Study Section (CIMG) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on clinical, population and integrative studies of the responses of the digestive system to trauma or surgery, and digestive system ischemia/reperfusion injury may be assigned to CIMG.

There are shared interests with Brain Injury and Neurovascular Pathologies Study Section (BINP) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on mechanisms of neural injury, related brain ischemia and traumatic brain injury may be assigned to BINP.

There are shared interests with Lung Injury, Repair, and Remodeling (LIRR) in the investigation of ischemia reperfusion injury. Grant applications that focus on tissue, organ/multiorgan and systemic ischemia reperfusion injury, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on lung epithelium injury, normal and abnormal lung permeability, and mechanisms of resolution, repair, and remodeling may be assigned to LIRR.

There are shared interests with Somatosensory and Pain Systems (SPS) in the investigation of pain. Grant applications that focus on mechanisms of action and pharmacology of general and local anesthetics, and pain management, including general and local anesthesia, and anesthetic side effects may be assigned to SAT. Applications that focus on the molecular biology, anatomy, physiology, and psychophysics of pain, analgesia and somatosensory systems may be assigned to SPS .

There are shared interests with Arthritis, Connective Tissue and Skin (ACTS) in the investigation of skin and integument wound healing and tissue regeneration. Applications that focus on tissue/organ regeneration, and remodeling of damaged tissues, and novel therapeutic interventions for maintenance or restoration of tissue function may be assigned to SAT. Applications that focus on biology, physiology, development and homeostasis of the skin, and skin disorders including dermatitis, keloids, fibrosis, psoriasis and bullous diseases may be assigned to ACTS.

There are shared interests with Bioengineering, Technology, and Surgical Sciences (BTSS) in the investigation of skin and integument wound healing and tissue regeneration. Applications that focus on tissue/organ regeneration, and remodeling of damaged tissues, and novel therapeutic interventions for maintenance or restoration of tissue function may be assigned to SAT. Applications that focus on the development of advanced tools and techniques, in the design, construction, and function of cellular and tissue-engineered constructs for surgical based interventions, regenerative medicine and wound healing may be assigned to BTSS.

There are shared interests with Transplantation, Tolerance, and Tumor Immunology (TTT) in the investigation of transplant rejection. Applications that focus on the transplant rejection associated with inflammation and innate immunity may be assigned to SAT . Applications that focus on the transplant rejection associated with immune tolerance and adaptive immunity may be assigned to TTT.