The Drug Discovery and Mechanisms of Antimicrobial Resistance [DDR] Study Section reviews applications that are concerned with the identification of novel antimicrobial, antifungal, and antiparasitic agents for the prevention and treatment of infectious diseases and the study of the evolution, mechanisms, and transmission of resistance.
- Drug discovery: drug target identification, characterization and validation; novel screening methods and assay development; molecular and medicinal chemical characterization of inhibitors; structure-guided drug design; preclinical studies using animal models
- Antimicrobial resistance: mechanisms and regulation of antimicrobial resistance; emergence, dissemination, and maintenance of resistance; strategies for the prevention of resistance; molecular characterization of resistant pathogens
- Development of procedures and/or instruments for the detection of antimicrobial resistant organisms, diagnosis, and treatments of infectious diseases
- Viral gene delivery, expression vectors, and phage therapy