The Kidney, Nutrition, Obesity and Diabetes Study (KNOD) study section reviews applications on the epidemiology, genetic epidemiology and prevention of kidney and urinary diseases, prostate, gastro intestinal and liver diseases, obesity (including the metabolic syndrome, developmental origins) and diabetes in human populations. Other areas considered include the epidemiology and determinants and outcomes of organ donation and transplantation and bariatric surgery. KNOD also reviews applications that consider diet, physical activity, environmental exposures and the microbiome on the disease conditions of interests.
- The distribution and patterns of diseases/conditions in human populations with respect to personal characteristics, place and time.
- Observational studies of determinants, predictors and biomarkers of the development, presence and prognosis of diseases/conditions. The factors of interest can include molecular, genetic, epigenetic, pharmacologic, behavioral, environmental, diet/nutrition, physical activity and social factors.
- Primary preventions including those evaluated by clinical trial (such as diet, physical activity and breastfeeding) with a focus on preventing disease or improving the outcomes or prognosis of diseases or conditions.
- Research designs and methodologies to address epidemiologic questions including cohort; case-control; prospective; longitudinal; retrospective; clinical trial; cross-sectional; surveillance; genetics; genome wide association studies (GWAS); epigenetics; genomics; gene-environment interactions; and molecular genetics.
- Assessment of body composition (anthropometrics or imaging), diet and physical activity. Physical activity assessments include self-report and objective measures using technology such as accelerometers and GIS and audits of the built and physical environment.