The Kidney, Nutrition, Obesity and Diabetes Study (KNOD) study section reviews applications on the epidemiology and genetic epidemiology of kidney, diabetes, obesity, urinary, gastrointestinal and liver diseases in human populations. The focus of interest can include molecular, genetic, epigenetic, pharmacologic, behavioral, environmental, microbiome, diet/nutrition, and physical activity.
Epidemiological research designs and approaches reviewed in KNOD include cohort, case-control, prospective, longitudinal, retrospective, clinical trial, cross-sectional, surveillance, genetics, epigenetics, genomics, transcriptomics, gene-environment interactions, genome wide association studies, metabolomics, molecular genetics and Omics technologies. Applications that use animal or other models or those seeking to determine mechanistic or physiologic pathways/functions of diseases are excluded.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Determinants, predictors and biomarkers of diseases and conditions related to diseases and conditions related to kidney, diabetes, obesity, urinary, gastrointestinal and liver diseases. These may be either risk or protective factors that include molecular, genetic, epigenetic, metabolomic, environmental, nutritional, physical activity, pharmacological, behavioral and social factors and the human microbiome.
- The geographic and secular distribution and patterns of development, and progression of conditions related to kidney, diabetes, obesity, urinary, gastrointestinal and liver, nutrition and physical activity.
- Randomized clinical controlled trials with a focus on treatment, prevention, and efficacy of intervention on specific disease conditions, and NOT the determination of mechanistic or biological pathways.
- Applications utilizing existing methodologies and apps for diet and physical activity assessment, refinement and/or validation, and reduction of measurement error, and NOT the development of new methodologies and/or apps/technology.
- Epidemiology and genetic epidemiology studies related to the determinants of bariatric surgery and outcomes.
- Determinants, predictors and biomarkers of liver and kidney disease transplantation and alloimmune outcomes.
Shared Interests and Overlaps
Biostatistical Methods and Research Design Study Section (BMRD): Applications focused on the design/development of novel statistical methodology/models are referred to BMRD while those focused on applying and validating existing statistical methodology/models are referred to KNOD.
Infectious, Reproductive, Asthma and Pulmonary Conditions (IRAP): IRAP and KNOD review applications focused on environment exposures during pregnancy related to obesity. If obesity outcomes are assessed on the progeny or in children in later life, the application is reviewed in KNOD, and in IRAP if the focus is on the perinatal period and pregnancy related outcomes.
Biomedical Computing and Health Informatics Study Section (BCHI): Applications focused on refinement or validation of existing apps for assessment of diet, physical activity and built environment are reviewed in KNOD. Those focused on the development, validation, and application of new mobile and wireless health (mHealth) and biosensor technology; integration of mobile sensor/device design, software or smartphone App development for assessment of diet, physical activity and the built environment are reviewed in BCHI.
There are shared interests with Human Studies of Diabetes and Obesity (HSDO) in the investigation of prevention of diabetes and obesity. Applications that focus on characterizing risk or protective factors of diabetes and obesity at the population level may be reviewed in KNOD, while those that focus on the identification of factors that modulate diabetes and obesity prevention and treatment may be reviewed by HSDO.
Psychosocial Risk and Disease Prevention (PRDP): Applications that focus on the prevention of the development and/or progression of obesity/diabetes are reviewed in KNOD while those that focus on social/psychosocial determinants of the onset and progression of obesity and social/psychosocial interventions to prevent or reduce risk are reviewed in PRDP. PRDP also reviews applications on the primary interventions of diet/nutrition and physical activity on obesity when the exposure is social/psychosocial in nature.
Genetics of Health and Disease (GHD): Applications related to genetics or epigenetics or genetic epidemiology of obesity, diabetic kidney, liver, gastrointestinal, and urinary conditions are reviewed in KNOD. Those focused on the discovery and development of genetic and genomic methodologies are reviewed in GHD.