The Kidney Molecular Biology and Genitourinary Organ Development [KMBD] Study Section reviews grant applications involving basic and applied aspects of normal and abnormal renal physiology, cell biology, transport biology, including osmoregulation and osmosensing, hormone action and signal transduction, vascular biology, genetic disorders, cell-matrix interactions, biophysics, and bioenergetics and basic processes underlying upper and lower genitourinary organ development.
The List of Reviewers lists all present, whether permanent or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Molecular biology and physiology of transport systems broadly relevant to renal function and disease, including acquired and inherited abnormalities; structure-function relationships; pharmacology relating to kidney function; ion channels and water channels of the kidney tubules.
- Renal cell physiology, cell signaling, and cell biology; protein trafficking and metabolism, regulation of gene expression, cell polarity, and other processes relevant to the function of renal cells.
- Disorders of tubular epithelial and endothelial cells as they relate to kidney diseases.
- Identification and characterization of genes that cause kidney diseases in humans and animal models; pathophysiology and cellular and molecular consequences of genetic disorders (including pathophysiology of polycystic kidney disease and disorders of tubular function), ciliopathies and ciliary structure of the kidney tubules, genetic models of polycystic kidney disease.
- Integrated aspects of disordered fluid, electrolyte, and acid-base homeostasis resulting from abnormalities in the transport systems.
- Blood pressure and extracellular fluid volume homeostasis; hormonal and autocoid regulation of renal function; influence of hypertension on vascular cells in the kidney; abnormal transport systems causing hypertension.
- Normal and abnormal development of organs of the upper and lower genitourinary tract which include kidney, ureter, bladder, prostate and genital development.
Shared Interests and Overlaps
There are shared interests between Development - 1 (DEV1) and KMBD in development of the kidney and genitourinary tract.
There are shared interests with Pathobiology of Kidney Disease [PBKD]. Basic cell and molecular biological studies of kidney function physiology and pathophysiology are typically reviewed by KMBD. The clinical manifestations of these processes are typically reviewed by PBKD.