The Urologic and Genitourinary Physiology and Pathology Special Emphasis Panel (SEP) ZRG1 DKUS-B (90) reviews applications that focus on function and dysfunction on the upper and lower urinary tract including the ureters, bladder and urethra; the male genital tract; and the visceral pelvis and pelvic floor musculature. Urologic or urogynecologic applications reviewed by this recurring SEP encompass a broad range of basic and translational areas.
Reviewed proposals address development and function of urologic and urogynecologic tissues and organs, including endocrine or neural influences; epidemiology, etiology and mechanisms of disease in these systems; diagnostic strategies and biomarkers; bioengineering; and medical and surgical management, including clinical trials.
The List of Reviewers lists all present, whether permanent or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
- Function of the bladder, ureter, and urethra and dysfunction of these and associated tissues, including conditions such as lower urinary tract symptoms (LUTS), interstitial cystitis/painful bladder and pelvic pain syndromes, overactive and underactive bladder, obstructive uropathy, diabetic uropathy and neurogenic and non-neurogenic incontinence.
- Studies of the development, epidemiology, diagnosis and management of primary congenital and acquired pediatric urological conditions affecting the bladder, ureters, urethra, and genital tracts, and secondary neurogenic conditions such as spina bifida.
- Infection and inflammation in the urinary tract, including studies of susceptibility, pathogenesis and treatment of bacterial, viral and fungal infections, and the role of the genitourinary microbiome in health and disease.
- Urolithiasis and nephrolithiasis, including studies of susceptibility, pathogenesis, and treatment of upper and lower urinary tract stones.
- Function and dysfunction of the prostate and associated non-cancerous conditions such as male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia.
- Male sexual function: physiology of penile erection, and the pathophysiology and treatment of erectile dysfunction.
- Studies of pelvic floor tissues in health and disease, including the pathogenesis and treatment of pelvic floor weakness and prolapse with associated bladder and/or bowel incontinence.
- Clinical and epidemiological studies, such as database analysis and clinical trials, to define risk factors, preventive strategies, biomarkers, and treatment of noncancerous urologic diseases.
Shared Interests and Overlaps
There are shared interests with Kidney, Nutrition, Obesity and Diabetes Study Study Section (KNOD), which focuses on clinical and genetic epidemiological studies that may include but not focus primarily on conditions affecting the urinary tract.
There are shared interests with Host Interactions with Bacterial Pathogens (HIBP), which focuses on the molecular basis of bacteria-host interactions and the host immune response, and with Bacterial Pathogenesis (BACP), which reviews applications that address determinants of bacterial pathogenesis. However, these study sections do not focus specifically on the pathogenesis of genitourinary infections.
Applications which focus on frank cancer of the urogenital tract are reviewed elsewhere.