The Clinical and Integrative Cardiovascular Sciences (CICS) study section reviews patient-oriented research involving the cardiovascular system and related regulatory organ systems. CICS focuses on studies which investigate the cardiovascular system of humans (and in some cases translational animal studies) including autonomic physiology and exercise cardiovascular studies. Applications may include cardiovascular studies in surgery and pediatrics.
Clinical trials that focus on mechanisms may be assigned to CICS, however, applications for randomized multi-center interventional clinical trials are not appropriate for CICS.
The List of Reviewers lists all present, whether permanent or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Human clinical studies including pediatric populations, appropriate translational animal studies, cardiovascular imaging, mechanisms and consequences of disease. Investigations may include coronary physiology and pharmacology, cardiac electrophysiology, regional circulation, hemodynamic studies, cardiac mechanics, and genetic considerations in cardiovascular studies. Disease states may include cardiac or vascular ischemia, heart failure/cardiomyopathy, metabolic syndrome, atherosclerosis, dyslipidemia, hypertension, obesity, diabetes, thyroid disease, general inflammation, or hypercholesterolemia.
- Modulation of cardiac/cardiovascular responses and adaptations including influence of acute and chronic exercise on metabolic function and cardiac, vascular smooth muscle, and vascular endothelial function(s). Pregnancy and aging may be considered modulatory influences.
- Neural control of the cardiovascular system including central and peripheral autonomic physiology, pharmacology, and receptor mechanisms in healthy and diseased populations.
- Clinical, population, or translational studies of the responses of the cardiovascular system to trauma or surgery including arrhythmias associated with cardiac surgery or cardiopulmonary bypass, cardiac sudden death, resuscitation, stenting, pacemakers, cardiovascular injury and repair, and myocardial ischemia/reperfusion injury.
- Environmental stresses and modifying conditions/stimuli including smoking, altitude, microgravity, heat, cold, bed rest/deconditioning, and environmental pollution in patients.
Shared Interests and Overlaps
There are shared interests between CICS and Cancer, Heart, and Sleep Epidemiology Study Sections – Panel A and Panel B (CHSA/B) in broad topics of cardiovascular diseases in humans. CICS reviews applications that have greater focus on clinical and mechanistic aspects of cardiovascular disease in humans. Applications that are more focused on the epidemiology of cardiovascular disease in human populations may be more appropriate for CHSA/B.
There are shared interests between CICS and Cardiac Contractility, Hypertrophy, and Failure (CCHF) in topics related to heart failure and cardiomyopathy. CICS reviews applications that focus on clinical aspects of heart failure and cardiomyopathy in humans and human samples. Applications that focus on basic and translational aspects of heart failure/cardiomyopathy, typically in animal models, may be more appropriate for CCHF.
There are shared interests between CICS and Hypertension and Microcirculation (HM) in topics related to blood pressure regulation, hypertension, neural control of the cardiovascular system, and micro- or regional circulation. CICS reviews applications that focus on clinical aspects of these topic areas in humans and human samples. Applications that focus on the basic and translational aspects of these topic areas, typically in animal models, may be more appropriate for HM.
There are shared interests between CICS and Atherosclerosis and Inflammation of the Cardiovascular System (AICS) in topics of atherosclerosis and inflammation of the vascular system. CICS reviews applications that focus on clinical aspects of atherosclerosis and vascular inflammation in humans and human samples. Application that focus on the basic and translational aspects of these topic areas in cellular and animal models may be more appropriate for AICS.
There are shared interests between CICS and Clinical and Integrative Diabetes and Obesity (CIDO) in topics of diabetes and obesity in humans. CICS reviews applications that are more focused on cardiovascular complications and endpoints related to diabetes and obesity. CIDO reviews non-cardiovascular research applications related to diabetes and obesity.
There are shared interests between CICS and Aging Systems and Geriatrics (ASG). Patient-oriented applications that involve modulation of cardiac and cardiovascular responses associated with aspects of aging or age-related diseases may be reviewed in ASG. Clinical applications focused on evaluating cardiac and cardiovascular conditions and diseases in geriatric populations may be appropriate for review in CICS.