The Hypertension and Microcirculation (HM) Study Section reviews applications involving basic and applied aspects of cardiovascular regulation with focus on the physiology of blood pressure regulation, the pathogenesis of hypertension and the microcirculation. It includes studies on cell surface receptors and signaling processes of various hormones, paracrines, and autocrines and their mechanisms of action as related to hypertension, integrated neural-humoral control of circulation, regional hemodynamics, lymphatic circulation, and microcirculation.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Mechanisms that regulate arterial blood pressure such as the roles of kidneys, central or peripheral nervous and endocrine systems, autocrine, paracrine, inflammatory or immunological factors.
- Pathogenesis of systemic hypertension involving cellular, molecular, and integrative mechanisms from the genome to whole animals or humans (excluding pulmonary hypertension).
- Neural and humoral control of the cardiovascular system in vertebrate animals including autonomic physiology involving reflex arcs and central mechanisms of cardiovascular regulation.
- Microcirculatory rheology, capillary pressure and permeability, mechanotransduction, fluid dynamics /mechanics, computational modeling, and bioengineering.
- Pathogenesis of microvascular diseases related to diabetic vasculopathy, stroke and other microvascular diseases such as Raynaud’s disease. Propulsion of lymph, lymphatic tone, and pathogenesis of lymphedema.
Shared Interests and Overlaps
There are shared interests with Vascular Cell and Molecular Biology (VCMB) . Applications looking at the cellular aspects of the blood-brain barrier, arterio-venous malformations may be assigned to VCMB. Applications involving stroke, microcirculation and flow related to hypertension may be assigned to HM.
There is a shared interest with Atherosclerosis and Inflammation of the Cardiovascular System (AICS) . Applications addressing the role of hemodynamics in atherosclerotic plaque formation and rupture and in aneurism formation and rupture may be assigned to AICS. Applications focusing on blood flow and circulation may be assigned to HM.
There are shared interests with Clinical and Integrative Cardiovascular Sciences (CICS) . Applications involving neural control of cardiovascular systems in humans and human hypertension may be assigned to CICS. Applications involving neural control of cardiovascular systems and hypertension in animal systems may be assigned to HM.
There are shared interests with Pathobiology of Kidney Disease (PBKD) . Applications involving hypertension-induced kidney injury may be assigned to PBKD. Applications involving the renal mechanisms of hypertension and blood pressure regulation may be assigned to HM.
There are shared interests with Brain Injury and Neurovascular Pathologies (BINP) (animal studies) and ANIE (human subject studies). Applications involving blood-brain barrier and vascular functions in development and treatment of neural injury may be assigned to BINP or ANIE. Applications involving stroke, microcirculation and flow related to hypertension may be assigned to HM.
There are shared interests and overlap with Cardiovascular Differentiation and Development (CDD) . Applications involving lymphatic development, lymphangiogenesis and lymphedema focusing on structure may be assigned to CDD. Applications focusing on lymphatic function, lymphatic tone, and pathogenesis of lymphedema may be assigned to HM.