The Cardiovascular and Hematological Sciences Small Business Special Emphasis Panel reviews grant applications related to the areas of cardiac and circulatory system devices, therapies and diagnostics and on all aspects of hematology including transfusion medicine and blood diseases. Projects are included at all levels of organization ranging from in vitro cell and tissue model systems through whole organisms, including humans. The stages of product development include technologies that have a prototype in-hand, through to the clinical research stage.
- Development of hematological diagnostic devices and assays.
- Development of blood components and transport containers.
- Storage of whole blood and its components, development of blood substitutes.
- Evaluation of transfusion medicine products and devices.
- Hematological stem cell culture, stem cell therapy and hematopoiesis.
- Therapy for hemoglobin disorders including gene therapy and anticoagulation therapy of pathologic hemostasis and thrombosis including hemophilia.
- Cardiology, cardiac function, heart failure, myocardial ischemia, reperfusion injury, stents, thrombosis/thrombolysis, imaging, monitoring systems.
- Electrophysiology, arrhythmias, sudden death, pacing, arrhythmia ablation.
- Cardiac and vascular surgery.
- Cell therapy and novel approaches to tissue repair/regeneration
- Emergency medicine, resuscitation, laboratory medicine, clinical chemistry, biomarkers.
- Lipid disorders, atherosclerosis.
- Biomedical and tissue engineering, biomaterials.
- Gene therapy and gene delivery systems, pharmacology, physiology.
Shared Interests and Overlaps
VH-10 and Medical Imaging (SBIB-10)have shared interests in topics related to medical imaging technologies. Applications which utilize established or newly developed imaging strategies applied within the context of cardiovascular systems research may be reviewed in CVRS-10. Applications which emphasize the development of novel imaging systems or strategies may be reviewed in SBIB-10.
VH-10 and Cardiovascular and Surgical Devices (SBIB-12)have shared interests in topics related to innovative research and technology development of biomedical devices and systems; they include devices and systems designed for a variety of cardiovascular disease processes including cardiac surgery, vascular surgery/interventions, electrophysiological procedures, critical/intensive care, drug/gene therapy delivery and a variety of other innovative technologies. While SBIB-12 will review applications.
There are shared interests with Small Business: Cell and Molecular Biology [IMST (15)]. Applications with new technologies for cell culture, stem cells, and cryopreservation of cells may be assigned to [IMST (15)]. Applications involving hematological stem cell culture and cryopreservation as it refers to blood products may be assigned to [VH (10)].
There are shared interests with Small Business: Biomaterials, Delivery, and Nanotechnology [BST (10)] and Small Business: Cell and Molecular Biology [IMST (15)]. Applications integrating cells into biomaterial constructs and/or studying the integration of biomaterials into cellular environments may be assigned to BST (10). Applications developing new cell-based technologies and assays may be assigned to IMST (15). Applications that involve developing assays or technologies for hematological applications may be reviewed in [VH (10)].