The Mechanisms of Cancer Therapeutics D – ATC (81)
Applications investigating the mechanisms-of-action of cancer therapies across drug classes encompassing established or repurposed cancer therapeutics. Studies focused on systems level translational modeling, drug synergy and therapeutic efficacy.
Review Dates
A roster for the panel will be posted here, at least 30 days prior to the review meeting
Topics
- Evaluation of the mechanism of action of established or repurposed cancer therapeutics spanning small molecules, peptide, protein, cellular, and genetic experimental therapeutics.
- Impact of drug treatments and combinations on epigenetic regulation, RNA processing, and post-translational modification.
- systems level translational modeling, including mathematical and computational methods for the investigation of therapeutic strategies.
