Special initiatives

• Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
• Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)
• Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)
• Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)
• Advanced Training in Artificial Intelligence for Precision Nutrition Science Research (AIPrN)  Institutional Research Training Programs (T32)
• Advancing communication strategies to support future HIV vaccine use (R01 Clinical Trial Optional)
• Advancing communication strategies to support future HIV vaccine use (R21 Clinical Trial Optional)
• Advancing Integrated Models (AIM) of Care to Improve Maternal Health Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Required)
• Advancing Integrated Models (AIM) of Care to Improve Maternal Health Outcomes among Women Who Experience Persistent Disparities (R21 Clinical Trial Optional)
• Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)
• Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)
• Autism Centers of Excellence: Networks (R01 Clinical Trial Optional)
• Basic Neurodevelopmental Biology of Circuits and Behavior (R01 Clinical Trial Not Allowed)
• Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
• Basic Research in Cancer Health Disparities (R03 Clinical Trial Not Allowed)
• Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
• Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)
• Biomedical Data Repository (U24 - Clinical Trials Not Allowed)
• Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed)
• Biomedical Technology Development and Dissemination Center (RM1 - Clinical Trial Not Allowed)
• Blood Brain Barrier Response to Antibodies Targeting Beta-Amyloid (R01 - Clinical Trial Not Allowed)
• BRAIN Initiative: Targeted BRAIN Circuits Planning Projects  TargetedBCPP (R34 Clinical Trials Not Allowed)
• BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed)
• Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed)
• Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)
• Career Enhancement Award to Advance Research on Firearm Injury and Mortality Prevention (K18 Independent Clinical Trial Not Allowed)
• CCRP Initiative: Countermeasures Against Chemical Threats (CounterACT) Therapeutics Discovery and Early-Stage Development (UG3/UH3 Clinical Trial Not Allowed)
• CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)
• Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)
• Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)
• Cellular and Molecular Mechanisms of Prion-Like Aggregate Seeding, Propagation, and Neurotoxicity in AD/ADRD (R01 Clinical Trial Not Allowed)
• Center for Coordination of Analysis, Science, Enhancement, and Logistics (CASEL) in Tobacco Regulatory Science (U54 Clinical Trial Not Allowed)
• Center for Rapid Surveillance of Tobacco (CRST) to Assess Changes in Use Behaviors, Product Marketing, and the Marketplace (U01 Clinical Trial Not Allowed)
• Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional)
• Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)
• Clinical Relevance of the Linkage between Environmental Toxicant Exposures and Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
• Collaborative Program Grant for Multidisciplinary Teams (RM1 - Clinical Trial Optional)
• Community Partnerships to Advance Science for Society (ComPASS): Coordination Center (U24 Clinical Trial Optional)
• Countermeasures Against Chemical Threats (CounterACT) Exploratory/Developmental Projects (R21 Clinical Trial Not Allowed)
• Data Management and Coordinating Center (DMCC) for the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRC) (U24 Basic Experimental Studies with Humans Requ
• Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed)
• Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R24 Clinical Trials Not Allowed)
• Development of the Fetal Immune System (R01 Clinical Trial Not Allowed)
• Dual Purpose with Dual Benefit: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species (R01)
• Early and Late Stage Clinical Trials for the Spectrum of Alzheimers Disease/Alzheimers Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional)
• Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01 Clinical Trial Not Allowed)
• Emergency Award: RADx-UP Community-Engaged Research on Rapid SARS-CoV-2 Testing among Underserved and Vulnerable Populations (U01 Clinical Trial Optional)
• Emergency Awards: RADx-UP - Social, Ethical, and Behavioral Implications (SEBI) Research on Disparities in COVID-19 Testing among Underserved and Vulnerable Populations (U01 Clinical Trial Optional)
• Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
• Emerging Global Leader Award (K43 Independent Clinical Trial Required)
• Enhancing the Use of the All of Us Research Programs Data (R21 Clinical Trial Not Allowed)
• Environmental influences on Child Health Outcomes (ECHO) Coordinating Center (U2C) (Clinical Trial Not Allowed)
• Environmental influences on Child Health Outcomes (ECHO) Data Analysis Center (U24) Clinical Trial Not Allowed
• Environmental influences on Child Health Outcomes (ECHO) Laboratory Core (U24) Clinical Trial Not Allowed
• Environmental influences on Child Health Outcomes (ECHO) Measurement Core (U24) Clinical Trial Not Allowed
• Ethical, Legal and Social Implications (ELSI) (Research R01 Clinical Trial Optional)
• Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21) (Clinical Trial Optional)
• Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03) Clinical Trial Optional)
• Evaluating the Impact of Pandemic Era related Food and Housing Policies and Programs on Health Outcomes in Health Disparity Populations (R01 Clinical Trial Optional)
• Expanding Collaborative Implementation Science to Address Social and Structural Determinants of Health and Improve HIV Outcomes (R01 Clinical Trial Required)
• Expanding Collaborative Implementation Science to Address Social and Structural Determinants of Health and Improve HIV Outcomes (R24 Clinical Trial Not Allowed)
• Expert-Driven Small Projects to Strengthen Gabriella Miller Kids First Discovery (R03 Clinical Trial Not Allowed)
• Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional)
• Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed)
• Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)
• Galvanizing Health Equity Through Novel and Diverse Educational Resources (GENDER) Research Education R25 (R25 Clinical Trial Not Allowed)
• Genomic Expert Curation Panels (U24 Clinical Trial Not Allowed)
• Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional)
• Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional)
• Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)
• Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa): Partnership for Innovation Research Projects (U01 Clinical Trial Not Allowed)
• Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa): Research Education Program (UE5 Clinical Trial Not Allowed)
• HEAL Initiative: Advancing Health Equity in Pain and Comorbidities (R61/R33 Clinical Trial Required)
• HEAL Initiative: Coordinated Pain Care in Health Care Systems Research Program  - Coordinating Center (U24 Clinical Trial Not Allowed)
• HEAL Initiative: Development and validation of virtual assessments to study children and caregivers in their natural environment (R01- Clinical Trial Not Allowed)
• HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
• HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL) (R01 Clinical Trial Required)
• HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL): Resource Center (U24- Clinical Trial Optional)
• HEAL Initiative: Opioid Exposure and Effects on Placenta Function, Brain Development, and Neurodevelopmental Outcomes (R01 Clinical Trial Not Allowed)
• HEAL Initiative: Opioid Exposure and Effects on Placenta Function, Brain Development, and Neurodevelopmental Outcomes (R21 Clinical Trial Not Allowed)
• HEAL Initiative: Research Studies to Develop and Implement Interventions to Prevent Opioid Misuse in Community Health Centers (R61/R33 Clinical Trial Required)
• HEAL Initiative: Secondary Analysis and Integration of Existing Data Related to Acute and Chronic Pain Development or Management in Humans (R21 Clinical Trials Not Allowed)
• HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
• Identification and Characterization of Bioactive Microbial Metabolites for Advancing Research on Microbe-Diet-Host Interactions (R01 Clinical Trial Not Allowed)
• Imaging, Biomarkers and Digital Pathomics for the Early Detection of Premetastatic Aggressive Cancer (R01 Clinical Trial Optional)
• Imaging, Biomarkers and Digital Pathomics for the Early Detection of Premetastatic Cancer and Precancerous Lesions Associated with Lethal Phenotypes (R01 Clinical Trial Optional)
• Impact of the Microbiome-Gut-Brain Axis on Alzheimer's Disease and Alzheimer's Disease-Related Dementias (R01 Clinical Trial Not Allowed)
• Implementation Research to Reduce Noncommunicable Disease (NCD) Burden in Low- and Middle-Income Countries (LMICs) and Tribal Nations During Critical Life Stages and Key Transition Periods (R01 Clinic
• IND-enabling Studies of Somatic Genome Editing Therapeutic Leads (U19, Clinical Trial Not allowed)
• Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)
• Innovative Research in Cancer Nanotechnology (IRCN) (R01 Clinical Trial Not Allowed)
• Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) (R43/R44 Clinical Trial Not Allowed)
• Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (STTR) (R41/R42  Clinical Trial Not Allowed)
• International Bioethics Research Training Program (D43 Clinical Trial Optional)
• International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)
• International Research Scientist Development Award (IRSDA) (K01 Independent Clinical Trial Required)
• International Research Scientist Development Award (IRSDA) (K01) Independent Clinical Trial Not Allowed
• Inter-Organelle Communication as a Platform to Interrogate the Interactions of Hallmarks of Aging (R01 Clinical Trial Not Allowed)
• Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
• Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional)
• Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R01 Clinical Trial Optional)
• Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R21 Clinical Trial Optional)
• Limited Competition:  NIGMS Mature Synchrotron Resources for Structural Biology (P30 - Clinical Trial Not Allowed)
• Limited Competition: Environmental influences on Child Health Outcomes (ECHO) Cohort Study Sites for Pediatric Follow Up. Clinical Trial Not Allowed (UG3/UH3)
• Limited Competition: Environmental influences on Child Health Outcomes (ECHO) Pregnancy and Pediatric Cohort Study Sites. Clinical Trial Not Allowed (UG3/UH3)
• Limited Competition: IDeA Regional Entrepreneurship Development (I-RED) Program (STTR) (UT2 Clinical Trial Not Allowed)
• Limited Competition: Research Resource for Human Organs and Tissues (U42 Clinical Trial Not Allowed)
• Limited Competition: Research Resource for the National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)
• Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
• Limited Competition: Transformative Research to Address Health Disparities and Advance Health Equity at Minority Serving Institutions (U01 Clinical Trial Optional)
• Mapping Interconnectivity Among Hallmarks of Aging under Lifespan Modifications (R01 Clinical Trial Not Allowed)
• Maternal Health Research Centers of Excellence Data Innovation and Coordinating Hub/Resource Center (U24 Clinical Trial Not Allowed)
• Maternal Health Research Centers of Excellence Implementation Science Hub/Resource Center (U24 Clinical Trial Optional)
• Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (R35 - Clinical Trial Optional)
• Maximizing Investigators' Research Award (R35 - Clinical Trial Optional)
• Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed)
• Measures and Methods for Research on Family Caregivers for People Living with Alzheimers Disease and Related Dementias (AD/ADRD) (R01 Clinical Trial Not Allowed)
• Measures and Methods for Research on Family Caregivers for People Living with Alzheimers Disease and Related Dementias (AD/ADRD) (R21 Clinical Trial Not Allowed)
• Mechanisms of Disparities in Chronic Liver Diseases and Cancer (R01- Clinical Trial Not Allowed)
• Mechanisms of Disparities in Chronic Liver Diseases and Cancer (R21- Clinical Trial Not Allowed)
• Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 -  Independent Clinical Trial Required)
• Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Not Allowed)
• Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed)
• Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)
• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRCs) (U54, Basic Experimental Studies Involving Humans Allowed)
• NIBIB Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)
• NIDA Program Project Grant Applications (P01 Clinical Trial Optional)
• NIH Directors Early Independence Awards (DP5 Clinical Trial Optional)
• NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional)
• NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional)
• NIH Directors Transformative Research Awards (R01 Clinical Trial Optional)
• NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Cohort (U54 Clinical Trial Optional)
• NIH HEAL Initiative: Coordinated Approaches to Pain Care in Health Care Systems (UG3/UH3 - Clinical Trial Optional)
• NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)
• NIH-NSF Ecology and Evolution of Infectious Diseases Program: A Joint Program (EEID) (R01)
• Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
• NSF/NIH Smart and Connected Health Program (R01)
• NSF/NIH The Collaborative Research in Computational Neuroscience (CRCNS) (R01)
• Open Competition: Environmental influences on Child Health Outcomes (ECHO) Pregnancy Cohort Study Sites. Clinical Trial Not Allowed (UG3/UH3)
• Pathway to Independence Award in Tobacco Regulatory Research (K99/R00  - Independent Clinical Trial Not Allowed)
• Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial  Required)
• Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)
• Pilot Projects Investigating Understudied G Protein-Coupled Receptors, Ion Channels, and Protein Kinases (R03 Clinical Trial Not Allowed)
• Pilot Studies for the Spectrum of Alzheimers Disease/Alzheimers Disease-Related Dementias and Age-Related Cognitive Decline (R61 Clinical Trial Optional)
• Planning Grant for Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions (D71 Clinical Trial Not Allowed)
• Planning Grant for Global Infectious Disease Research Training Program (D71 No Clinical Trials Allowed)
• Platform Clinical Trials of Genome Editors in Multiple Diseases (UG3/UH3, Clinical Trial Required)
• Prodromal Synaptic and Circuit Changes that Contribute to AD/ADRD Onset and Progression (R01 Clinical Trial Not Allowed)
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
• Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (UG3/UH3 Clinical Trial Required)
• Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)
• Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional)
• Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R01 Clinical Trials Not Allowed)
• Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R21 Clinical Trials Not Allowed)
• Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
• Research to Improve Native American Health (R21 Clinical Trials Optional)
• Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)
• Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed)
• Small Grants to Enhance the Use of the All of Us Research Programs Data (R03 Clinical Trial Not Allowed)
• Small Research Grant Program for the Next Generation of Clinical Researchers in AD/ADRD Research: Area of Focus Basic Science (R03 Clinical Trials Not Allowed)
• Small Research Grant Program for the Next Generation of Clinical Researchers in AD/ADRD Research: Area of Focus Systems Biology (R03 Clinical Trial Not Allowed)
• Somatic Cell Genome Editing Program Translational Coordination and Dissemination Center (TCDC) (U24 - Clinical Trial Not Allowed)
• Somatic Mosaicism across Human Tissues (SMaHT) Program:  Tool Development Projects (UG3/UH3 Clinical Trial Not Allowed)
• Somatic Mosaicism across Human Tissues (SMaHT) Program: Data Analysis Center (UM1 Clinical Trial Not Allowed)
• Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed)
• Somatic Mosaicism across Human Tissues (SMaHT) Program: Organizational Center (U24 Clinical Trial Not Allowed)
• Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (U24 Clinical Trial Not Allowed)
• Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional)
• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
• Studies of Cytosolic DNAs in the Interactions of Aging Hallmarks (R01 Clinical Trial Not Allowed)
• Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R01 Clinical Trial Not Allowed)
• Technologies and Assays for Therapeutic Genome Editing INDs (U01, Clinical Trial Not Allowed)
• The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
• Time-Sensitive Opportunities for Health Research (R61/R33 Clinical Trial Not Allowed)
• Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54  Clinical Trial Optional)
• Tobacco Regulatory Science (R01 Clinical Trial Optional)
• Toward ElucidAting MechanismS Contributing to HIV Reservoirs in NIDDK-relevant Tissues (Cure TEAMS) (R01 Clinical Trial Optional)
• Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)
• Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R01 Clinical Trial Optional)
• Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R21 Clinical Trial Optional)