Therapeutic Development for CNS Injuries, Neurovascular, and Neurological disorders – BN (13)
This review panel reviews applications dealing with basic, preclinical, and clinical aspects of drug discovery in treatment of conditions including the CNS injuries, stroke, neurovascular disorders, and neurological disorders such as multiple sclerosis, chronic pain, and epilepsy. Approaches are those of medicinal chemistry and pre-clinical therapeutic development, toxicology, and some clinical studies to establish proof-of-principle for new or repurposing existing drugs. The arrange of therapeutic formats include small molecule drugs and biologics such as molecular manipulation and engineering, gene and stem cell therapies, and proteins/neuropeptides that interact with and modulate neuroreceptors, transporters and transducers.
Review Dates
Topics
- Spinal cord injury and traumatic brain injuries, and their sequelae and comorbidities
- Stroke and ischemic brain injuries
- Brain blood vascular, glymphatic circulation and non-stroke vascular abnormalities, including Vascular Contributions to Cognitive Impairment and Dementia (VCID)
- Multiple sclerosis and other neuroautoimmune diseases
- Chronic pain, migraine, neuropathic pain, and peripheral neuropathies
- Epilepsy and hyperexcitability induced CNS injuries
