Special Emphasis Panel on Mechanisms and Pathology of Pain and Itch – ZRG1 NPA (87)
Special Emphasis Panel on neuroscience and pathology of Pain and Itch reviews applications that study the neuroscience behind mechanisms of pain and itch. The applications reviewed in this panel can be mechanistic, preclinical and translational. Applications can involve mechanisms underlying pain and pain management strategy, computational modeling, relevant animal models and ex-vivo models, signaling pathways underlying pain/itch.
Topics
- Pain/pain management related to neuropathy, and neuronal injury
- Pain related to neuroinflammatory diseases and disorders
- Neurobiology of neuroma and cancer related pain
- Neuroimmunology driving pathways of pain and itch
- Pharmacological and non-pharmacological approaches to management of pain and itch
- Assessment of analgesics and drugs in pain management
- Discovery of novel pharmacological targets for pain
Shared Interests and Overlaps
There is significant shared interest between NPI and NPA-87. Applications on different aspects of neurobiology of pain and itch that are reviewed in both panels. NPI does mechanistic, clinical and translational applications in this area, while NPA87 focuses on preclinical studies and development and testing of analgesics.
There is shared interest between MNG and NPA-87 in reviewing applications on genetics. Applications that investigate the genetics or epigenetics of pain are reviewed in NPA-87, while applications focused on gene delivery methods may be reviewed by Molecular Neurogenetics (MNG).
There is shared interest between NPA-87 and NMB in applications involving analgesics and pain medication. Applications on pain mechanism and modulation are reviewed in NPA-87. Applications related to motivated behaviors, such as mediation of drug and other types of reward, mechanisms of tolerance, dependence, withdrawal, and sensitization may be reviewed by Neurobiology of Motivated Behavior (NMB).
There is shared interest between NPA-87 and on applications that study somatosensation. Somatosensation when focused on pain and itch are reviewed in NPA87.Somatosensation, when not focused on pain or itch, are more appropriate for Sensory-Motor Neuroscience (SMN) or Neuroscience of Interoception and Chemosensation (NIC)
There are shared interests with Surgery, Anesthesiology and Trauma (SAT) and NPA-87 in the investigation of pain. Grant applications that focus on mechanisms of action and pharmacology of general and local anesthetics, and pain management, including general and local anesthesia, and anesthetic side effects may be assigned to SAT. Applications that focus on the molecular biology, anatomy, physiology, and psychophysics of pain and analgesia may be assigned to NPI.
There are shared interests between MCNP and NPA-87 in the neurobiology of pain with Molecular Cellular Neuropharmacology (MCNP). Applications that emphasize the neurobiology of pain, analgesia and itch are reviewed in NPI. Applications that emphasize cellular and molecular mechanisms of substances used to treat these disorders are reviewed in MCNP.
