Small Business: Assay Development, Drug Discovery Tools and Imaging – NV (16)
The topics covered include applications that seek to develop assays, model systems, tools and reagents to probe the biological and/or physiological underpinnings of psychiatric, neurological or neurodegenerative diseases. Model systems may include transgenic, cell culture, lab on a chip as well as organinoid systems. New applications of imaging methodologies and ancillary tools for diagnostics and research applications are also reviewed in this study section.
With respect to development and aging, studies may examine the basic biology of stem cells as well as strategies for their culture and differentiation in vitro and vivo. Novel strategies for animal cloning as well as the use of genetic approaches to address developmental questions are also covered.
The methodologies which are covered include, but are not limited to cellular/molecular, genetic/genomic, chemical, electrophysiological, imaging, computational as well as digital assisted technologies.
Review Dates
Topics
- Assay systems using cellular/molecular, chemical, electrophysiological, behavioral, imaging, or digital-assisted methodology.
- Preclinical models for neurological and neuropsychiatric disorders, development or aging. E.g. model organisms, cell cultures, organ-chips, etc.
- New models of aging: including transgenic, animal and cellular.
- Tools, reagents and devices that facilitate the study of biological/physiological underpinnings or the development of therapeutics for disorders in the nervous system, development, or aging.
- Development and applications of computational modeling and AI tools in neural therapeutic development and testing.
- the development of technology including imaging and recording techniques; analytical and system control software are covered.
- Devices may include development of imaging and recording techniques, analytical and system control software
- Development of imaging tracers for use in diagnosis of neuro system diseases.
- Microscopy imaging and analysis
- Biomarkers utilizing Imaging technologies
