Special Emphasis Panel for Combined Cardiovascular Biology and Hematology – IVBH (81)
Will review applications from basic research through translational studies. The SEP can review applications ranging from abdominal aortic aneurysms, hypertension (neurogenic, vascular and renal), microcirculation, cardiomyopathies/cardiomyocytes and hematopoiesis (erythropoiesis and megakaryopoiesis).
Review Dates
A roster for the panel will be posted here, at least 30 days prior to the review meeting
Topics
- Aortic aneurysms, vascular wall pathophysiology
- Neurogenic hypertension, including vascular and renal hypertension.
- Microcirculation and tissue transport processes.
- Coronary vascular biology and disease
- Cardiomyopathies: Impact of diabetes, systemic metabolic disorders, immunological and microbial mediators, and infectious diseases.
- Cardiac myocytes: Structural biology, contractile functions, and mechanical stress generation on cells and tissues.
- Hematopoiesis and hematopoietic stem cell regulation including the impact of environmental factors, metabolites, neural inputs, circulating factors, diabetes and coronary artery disease, immunological mediators, microbial contributors, infectious agents, bone marrow microenvironment and vascular niche.
Shared Interests and Overlaps
With Atherosclerosis and Vascular Inflammation (AVI)have shared interests in vessel wall pathophysiology. Applications involving aortic aneurysms will be reviewed in CCBH sep . Applications that involve other aspects of vessel wall pathology may be reviewed in AVI.
With and Hemostasis, Thrombosis, Blood Cells and Transfusion Study Section (HTBT) have shared interests in hematopoiesis and hematopoietic stem cell regulation. Applications that involve the impact of environmental factors, neural inputs, and circulating factors will be reviewed in the CCBH sep. Applications that emphasize the mechanism of action, the involvement of blood cells in disease and all non-clinical transfusion related applications will be reviewed in HTBT.
CCBH and Basic Biology of Blood, Heart and Vasculature - BBHV have shared interests in hematopoiesis, hematopoietic stem cell regulation, cardiac myocytes, cardiomyopathies, and endothelial cell biology. Applications that involve the impact of immunological and microbial mediators, infectious agents, systemic metabolic disorders, and coronary vascular biology will be reviewed in CCBH. Applications that emphasize molecular and cellular biology of blood, vascular, and cardiac cells will be reviewed in BBHV. Due to the overlap between the two CCHB and BBHV applications will be moved between the two panels depending on the amount of basic vs translational science in the application.
CCBH and Integrative Myocardial Physiology/Pathophysiology A, B, C (MPPX) have shared interests in the area of myocyte cardiac hypertrophy, myocyte interactions, cardiomyocyte contractile function as well at metabolism and energetics aspects of heart disease. Applications that emphasize these functions on humans will be reviewed in MPPX. Applications that emphasize these functions on cells and tissues will be reviewed in CCBH.
