Special Emphasis Panel for Integrative Myocardial Physiology/Pathophysiology C – RCCS (80)
The Special Emphasis Panel for Integrative Myocardial Physiology/Pathophysiology C reviews basic and applied/translational applications generally focused on mechanisms which regulate normal and pathologic myocardial function with an emphasis on aspects of cardiac growth and recovery, including dysfunction following aging, disease and/or injury. Topics include cardiovascular tissue repair. Representative methods and experimental strategies may include but not exclusive to electrophysiology, stem cells/bioengineered tissue, model systems, genetics, genomics, proteomics, computational and systems biology.
Review Dates
A roster for the panel will be posted here, at least 30 days prior to the review meeting
Topics
- Basic molecular, genetic and cellular mechanisms related to cardiomyocyte /non-cardiomyocyte growth, proliferation, metabolism and apoptosis; receptor signaling; transcriptional pathways; inflammatory/ cytokine-mediated processes.
- Cardiac Tissue repair; stem cells; cell type differentiation and regeneration following injury; metabolic bioenergetics associated with health and dysfunction
- Validation of engineered tissue for support, repair, regeneration of compromised tissue (diseased, injured)
- cardiovascular toxicity
- Metabolic bioenergetics associated with health and dysfunction
- Cardiac Tissue repair; stem cells; differentiation and regeneration following injury