This panel reviews patient-centered behavioral interventions focused on the management and treatment of mental health disorders in adults, children, and aging individuals, to improve long-term outcomes and recovery of function. Across mental health conditions, treatment approaches may focus on managing residual symptoms/impairment, consolidating and maintaining gains from initial treatment, preventing relapse, and promoting treatment adherence. Applications may propose a variety of treatment approaches, including pharmacological approaches, psychological or behavioral processes (e.g., cognitive control, stress regulation), devices, psychotherapies, and case management services. Therapeutic interventions to improve symptoms, functional outcomes, and/or care for individuals with Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) are also included. All applications are in human populations. Applications proposing molecular, cellular, genetic, and physiological treatment approaches are not included. Applications proposing to increase access, use, reach, adoption, and implementation of mental health services are not included.

Review Dates

A roster for the panel will be posted here, at least 30 days prior to the review meeting

Topics


  • Treatment of mental health conditions that are chronic or relapsing (e.g., anxiety disorders, mood disorders, ADHD, psychotic disorders); continuation treatments (psychosocial, pharmacological) that strengthen and extend gains achieved during initial treatment, or specifically target residual symptoms/impairments associated with relapse/ongoing dysfunction;  
  • Treatments for “gateway conditions” (e.g., ADHD, anxiety, first episode psychosis) in order to reduce risk for common downstream comorbidities (e.g., substance use disorders, suicidality);
  • Behavioral applications proposing treatment for acute mental health disorders (management of an episode, suicide, crisis, or worsening of mental illness that requires intense treatment) to manage symptoms, prevent harm, and stabilize functioning;
  • Post-acute treatment approaches including pharmacological and device-based treatment approaches to address residual symptoms and impairment and reduce the risk for relapse and ongoing dysfunction;
  • Multi-modal or integrated intervention approaches, such as combination treatments or sequenced pharmacological, psychosocial approaches to evaluate if combination or sequencing results affects outcomes.
  • Treatment strategies to optimize longer-term pharmacotherapy/prevent long-term adverse effects of treatment and reduce unnecessary polypharmacy.

 

Last updated: 02/26/2026 10:39