Neurological, Mental and Behavioral Health – NMBH

Topics

• Studies addressing the incidence, prevalence, progression and consequences of neurological diseases and phenotypes in large populations ranging from neurodevelopmental disorders to neurological conditions related to aging  
• Studies addressing the incidence, prevalence, progression and consequences of mental health, mental disorders and related phenotypes, behavioral health and behavioral disorders including substance use disorders in large populations
• Studies addressing the incidence, prevalence, progression and consequences of communication and visual disorders and related traits in large populations including abnormalities of hearing, sight, balance, taste, smell, voice, speech and language
• Studies of incidence, prevalence and determinants of co-morbidities and multi-morbidities with neurological, mental and behavioral conditions and disorders in large populations
• Studies examining the effects of environmental and other exposures on incidence, progression, and outcomes related to neurological, mental and behavioral conditions and disorders in large populations, especially with a focus on the disease or disorder outcome rather than the exposure
• Applications may use methodologies and study designs including cohort, case-control, prospective, longitudinal, retrospective, clinical trial, cross-sectional, surveillance, omics (i.e. genomics, transcriptomics, proteomics, metabolomics, epigenomics, metagenomics) and assessment of gene-environment interactions

Shared Interests and Overlaps

There are shared interests in age-related conditions such as Alzheimer’s disease with Aging, Injury, Musculoskeletal and Rheumatologic Disorders (AIMR).  Applications that primarily focus on characterizing the determinants of neurological diseases and disorders are reviewed in NMBH. Applications that emphasize the process of aging and how aging affects the development, progression and consequences of neurological disorders and conditions are reviewed in AIMR.

There are shared interests in substance use with a population-based focus with Lifestyle and Health Behaviors (LHB). Applications that emphasize behavioral health conditions or disorders as the health outcome, for example applications focusing on substance use disorders, are reviewed in NMBH. Applications that focus on health behaviors as an exposure or health outcome are in LHB, for example applications focused on substance use or how substance use affects other health outcomes.

There are shared interests in social or environmental epidemiology applications that assess behavioral, mental and neurological outcomes with Social and Environmental Determinants of Health (SEDH).  Applications that focus on behavioral, mental and neurological health conditions and disorders at the population level incorporating environmental and/or social exposures as risk factors can be reviewed in NMBH. Applications that focus on the characterization of environmental and/or social determinants or exposures that contribute to behavioral, mental and neurological health conditions at the population level can be reviewed in SEDH.

There are shared interests in neurodevelopmental outcomes of children with Reproductive, Perinatal and Pediatric Health (RPPH). Applications that focus on neurodevelopmental outcomes in children at the population level are reviewed in NMBH. Lifecourse applications that focus on the relationship between prenatal exposures and neurodevelopmental outcomes in the children at the population level are reviewed in RPPH.

There are shared interests in studying the genetic predisposition to disease using population-based samples with Genetics of Health and Disease (GHD). Applications that emphasize how these factors contribute to health outcomes in human subpopulations are reviewed in NMBH. Applications that emphasize discovery of genetic, genomic, epigenomic elements and molecular signatures are reviewed in GHD.

There are shared interests in cognitive and behavioral outcomes in aging-associated neurodegeneration with Cognitive Disorders and Brain Aging (CDBA). Applications that emphasize the distribution of these outcomes among human populations are reviewed in NMBH. Applications that emphasize investigating the mechanisms underlying the outcome are reviewed in CDBA. 

There are shared interests in behavioral and psychiatric conditions with Child Psychopathology and Developmental Disabilities (CPDD). Applications that focus on non-population-based/epidemiological applications that emphasize the neurobiological foundations underlying neurodevelopmental or psychiatric disorders in humans in early development are reviewed in CPDD. Applications that emphasize studies of the etiology, determinants, distribution, and outcomes of neurological, mental, and behavioral conditions and disorders from a population health perspective are reviewed in NMBH. Applications that emphasize epidemiological study designs to examine determinants, predictors, and biomarkers associated with behavioral, psychiatric, and substance use disorders exclusively in human subpopulations are reviewed in NMBH. 

There are shared interests in behavioral and psychiatric conditions with biobehavioral processes with Mechanisms of Emotion, Stress and Health (MESH). Applications that emphasize epidemiological study designs to examine determinants, predictors, and biomarkers associated with behavioral, psychiatric and substance use disorders exclusively in human subpopulations are reviewed in NMBH. Applications that emphasize the neurological foundations underlying these conditions in both experimental animal models and humans are reviewed in MESH.

There are shared interests in neurological, mental, and behavioral conditions and disorders with Neural Basis of Psychopathology, Addictions, and Sleep Disorders (NPAS). Applications that emphasize these disorders from a large population health perspective, particularly those characterizing the effect of genetic, epigenetic, biological, and environmental factors on the risk, development, and progression of these brain-related conditions and disorders are reviewed in NMBH. Applications that emphasize clinically applications addressing the pathophysiology or the underlying neurobiological or neuropsychiatric mechanisms of these conditions and disorders are reviewed in NPAS.