Special Emphasis Panel on Clinical and Translational neurodevelopment and neuropsychiatry – ZRG1 CN-82

Topics

• Preclinical and clinical studies on developmental disorders of nervous system (brain and spinal cord) in pediatric and adolescent populations.
• Mechanistic aspects of developmental disorders or the brain and nervous system (genetic, epigenetic, metabolic and environment driven).
• Mechanisms driving developmental and neuropsychiatric disorder across lifespan.
• Translational and clinical basis of biological, social and/or environmental basis of behavioral disorder.
• Computational approaches related to developmental and neuropsychiatric disorders in neonatal and pediatric populations.
• Animal and organoid models of developmental disorders of the nervous system.
• Hereditary developmental disorder/rare genetic disorder throughout lifespan.
• Clinical, preclinical and mechanistic studies underlying addiction and behavioral disorder (including but not limited to stress, anxiety, mood) that have a neurobiological focus/outcome.

Shared Interests and Overlaps

There is a significant shared interest with the (DBD) on developmental disorders. Applications that focus on mechanistic, preclinical and clinical aspects developmental disorders of the brain, in-utero, abnormalities in brain structure, function and connectivity are reviewed in DBD while mechanistic, preclinical and clinical, developmental disorders of the nervous system are reviewed in CN-82. Applications on genetic and epigenetic mechanisms of developmental disorders in neonatal and pediatric population are reviewed in DBD while CN82 reviews these topics when in an adolescent or young adult population.

There is a significant shared interest with (NPAS) and (PMDA) on neuropsychiatric and mental disorders. Applications that are focused on human and clinical aspects of psychiatric behavior, addiction and sleep are reviewed in NPAS. The applications that emphasize on cellular, mechanistic and preclinical studies on neurobiology of psychiatric and mental disorders are reviewed in PMDA. Clinical, preclinical and mechanistic studies driving developmental and neuropsychiatric disorder in adolescence and adulthood are reviewed in CN-82

There are shared interests in the areas of neuropsychiatric and sleep disorders with (ALP). Applications that emphasize more on preclinical and clinical aspects of structural and mechanistic aspects and the etiology, neural mechanisms, diagnosis of neuropsychiatric disorders in are reviewed in CN-82. Applications that emphasize emotional, and/or behavioral aspects of psychopathology are reviewed in ALP. 

There is some shared interest regarding effects of chronic exposure to alcohol and alcohol dependence with (NAL). Applications that emphasize on the negative consequences of alcohol exposure throughout development and in adulthood, rather than motivational aspects of alcohol addiction are reviewed in NAL. Applications that emphasize etiology, pathophysiology, and treatment of alcoholism and are reviewed in CN 82.

There is some shared interest with (NMB). Applications that focus on the neurobiology and circuitry of motivated behavior are reviewed in NMB while applications that model psychiatric disorders, and examine how these mediate cognitive, behavioral, emotional, social, and learning abnormalities may be better suited for review by CN82

There are shared interests in the neurobiological and neuropsychological mechanisms of substance use and addiction with (ARM). Applications that emphasize primary outcomes that are behavioral or psychosocial are reviewed in ARM. Applications that emphasize the neurochemical, neuroendocrine, or biochemical mechanisms of psychopathology, including addiction, are reviewed in CN 82.