The Neurotoxicology and Alcohol [NAL] Study Section reviews applications that address the effects of environmental toxicants or alcohol on the central nervous system in animal models and humans.
Environmental toxicants include air pollution (diesel exhaust, organic compounds, ambient particulate matter) metals, plasticizers, pesticides, and others. The emphasis of the alcohol research in this study section is on the negative consequences of alcohol exposure throughout development and in adulthood, rather than motivational aspects of alcohol addiction. The approaches include molecular, cellular, pharmacological, physiological, behavioral, neuroimaging, genetic, and computational.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Neuroteratology: effects of acute or chronic prenatal or early exposure to environmental toxins on development of the central nervous system.
- Fetal alcohol spectrum disorders: anatomical and behavioral effects of prenatal alcohol exposure on the central nervous system, and associated phenotypes.
- Neurodegeneration: effects of acute or chronic exposure to neurotoxins or alcohol on oxidative stress, neuroinflammation, neurodegeneration, cognitive deficits, motor impairment and development of neurodegenerative diseases (e.g. Parkinson’s disease, Alzheimer’s disease, ALS, etc.).
- Gene environment interaction: genetic factors responsible for increased vulnerability to neurotoxicants or alcohol use disorder.
- Alcohol dependence: epigenetic, molecular, and cellular effects of alcohol exposure; synaptic, structural, and behavioral adaptations resulting from chronic or repeated alcohol exposure, and associated with symptoms of alcohol withdrawal and negative affect, such as anxiety and depression.
- Interaction between stress and alcohol: maladaptive responses to acute, chronic or developmental stress associated with increased alcohol consumption and relapse to alcohol abuse.
Shared Interests and Overlaps
Applications with a focus on behavioral mechanisms of alcohol abuse, such as discriminative and reinforcing effects of alcohol, social influences, and behavioral economic approaches may be reviewed by Biobehavioral Regulation, Learning and Ethology Study Section [BRLE].
Applications examining the reward circuitry and motivational aspects of alcohol addiction may be reviewed by Neurobiology of Motivated Behavior (NMB).
Applications including alcohol or neurotoxicology, but focused on neuroimmunology may be reviewed in Neuroendocrinology, Neuroimmunology, Rhythms and Sleep Study Section [NNRS].
Clinically-oriented applications focused on etiology, pathophysiology, and treatment of alcoholism may be reviewed by Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS).
Applications focused on developmental disabilities not associated with exposure to alcohol or environmental toxins will not be assigned to NAL, and may be reviewed by Child Psychopathology and Developmental Disabilities (CPDD).
Applications focusing on the effects of environmental toxicants outside the central nervous system will not be assigned to NAL, and may be reviewed by Systemic Injury by Environmental Exposure [SIEE].