Population-based Research in Infectious Disease – PRID

Topics

• Studies on a range of Infectious diseases to understand their effect on human populations or sub-populations including bacterial, fungal, parasitic, vector-borne, zoonotic and viral diseases with attention to emerging and drug-resistant infections
• Assessment of human genetic, epigenetic, social, biological, behavioral and environmental factors that affect susceptibility to infection, disease progression and severity of infectious disease outcomes in human populations. This includes identification of biomarkers tracing both natural infection and responses to infectious disease control efforts at the human population level.  
• Surveillance studies characterizing the prevalence, incidence and outcomes of infectious diseases in human populations and subpopulations as well as different settings including community or healthcare environments
• Epidemiological studies to assess changes in infectious disease transmission dynamics and burden in human populations over time
• Applications may use methodologies and study designs including cohort, case-control, prospective, longitudinal, retrospective, clinical trial, cross-sectional, and surveillance and monitoring systems. Applications may use variable data types including clinical, behavioral, social, environmental, omics (i.e. genomics, transcriptomics, proteomics, metabolomics, epigenomics, metagenomics) and assessment of gene-environment interactions

Shared Interests and Overlaps

There are shared interests in the epidemiology of infectious diseases and characterization of immune responses with Etiology, Diagnostic, Intervention and Treatment of Infectious Diseases (EDIT). Applications that are intended to inform on pathogen characteristics or that employ population-level analyses to inform on fundamental human immune responses to pathogens are reviewed in EDIT. Applications that are intended to inform on population-level attributes, including immunological, genetic, epigenetic, behavioral, social and environmental factors determinants of infectious disease may be reviewed in PRID.

There are shared interests in infectious disease transmission modeling with Analytics and Statistics for Population Research Panel B (ASPB). Applications that emphasize the application of infectious disease modeling and geospatial analysis methodology to characterize infectious disease transmission in large human populations are reviewed in PRID. Applications that emphasize the development of infectious disease dynamic modeling and geospatial analysis methodology to be applied in future population health studies are reviewed in ASPB.

There are shared interests in the environmental and social determinants of infectious disease dynamics with Social and Environmental Determinants of Health (SEDH). Applications that primarily focus on infectious disease transmission and outcomes with consideration of social and environmental determinants can be reviewed in PRID. Applications that focus on the characterization of environmental and/or social determinants or exposures that influence infectious disease transmission and outcomes at the population level can be reviewed in SEDH.

There are shared interests in infectious disease with other study sections in the Epidemiology and Population Health Branch. Applications that emphasize the infectious disease process in different human populations including the effects of other diseases and conditions on infectious disease transmission and outcomes are reviewed in PRID. Applications that emphasize infection as the exposure and the focus of the application is on the effects of current or past infection on noncommunicable disease or other health outcomes at the population level are reviewed in other study sections in the Epidemiology and Population Health Branch.

There are shared interests in infectious disease in humans with study sections in Immunology and Infectious Diseases A (IIDA) and Immunology and Infectious Diseases B (IIDB) Review Branches. Applications that seek to identify biomarkers that are associated with disease incidence, progression and treatment outcomes at the human population level to better understand how infections progress in different human populations are reviewed in PRID. Applications that seek to define the mechanisms underlying host-pathogen interactions at the intracellular and cellular levels as well as define the immune response to infection at the individual human level with laboratory-based studies are reviewed in other immunology and infectious disease study sections. 

There are shared interests in studying the genetic predisposition to disease using population-based samples with Genetics of Health and Disease (GHD). Applications that emphasize how these factors contribute to health outcomes in human subpopulations are reviewed in PRID. Applications that emphasize discovery of genetic, genomic, epigenomic elements and molecular signatures are reviewed in GHD.

There are shared interests in population-level analyses of drug resistance with Anti-Infective Resistance and Targets (AIRT). Applications that focus on human populations are reviewed in PRID. Applications that emphasize studies of microbe populations are reviewed in AIRT.

There are shared interests in the transmission of zoonotic and vector-borne diseases with Transmission of Vector-Borne and Zoonotic Diseases (TVZ). Applications that emphasize the pathogen life cycle, host-pathogen interactions at the individual level, or zoonotic transmission of pathogens may be reviewed in TVZ.  Applications that emphasize the transmission of zoonotic and vector-borne diseases between human populations may be reviewed in PRID.