Small Business: Diabetes, Metabolism, Nutrition and Obesity – EMS (10)
The EMS Small Business standing SEP [EMS (10)] reviews SBIR/STTR applications in areas concerned with the endocrine, metabolic and nutritional basis of diabetes and obesity.
Specifically metabolic, molecular and neuroendocrine basis of energy expenditure and weight management, pathogenesis of obesity and diabetes and their management utilizing new and improved therapeutic strategies, bioengineering approaches in monitoring metabolic and nutritional biomarkers. In general EMNR S10 covers science range of IPOD, INMP, CADO and CIDO study sections and invokes clinical trials and studies in mammalian systems.
Review Dates
Topics
- Energy balance, expenditure, thermogenesis, physical activity, exercise and bariatric surgery in the context of the pathogenesis or treatment of obesity and diabetes.
- Nutrient, Neutraceuticals and dietary intervention in the treatment of these metabolic and endocrine disorders including diabetic complications and peripheral artery disease.
- Adipocyte functions, adiponectin secreatagogues, inflammation and anti-inflammatory agents. Stem cell delivery for adipose tissue repair.
- Devices development and testing in clinical management/ treatment of metabolic and endocrine disorders and diabetic complications.
- Diagnostic assay kits and automated assays for regulators of insulin synthesis.
- Neuroendocrinology and pharmacological interventions in other endocrine disorders. Such as acromegaly, thyroid and growth hormone disorders in adult, pediatric and neonatal population.
- Biosensor (e.g., glucose sensors-chemical, optical and electrochemical etc.) to effect continuous glucose monitoring for effective treatment of diabetes; drug and nutrient delivery across cell and tissue systems. Differentiation, development, growth, and function of pancreatic islets, artificial pancreas. Beta cell viability and methods at optimization for use in islet transplantation and cell based therapies.
Shared Interests and Overlaps
- Interdisciplinary Molecular Sciences and Training IRG IMST
- Digestive Kidney and Urological Systems IRG DKUS
- Musculoskeletal, Oral and Skin Sciences IRG MOSS
There are shared interests between the small business panels in Endocrine and Metabolic Systems Review Branch (EMS) and Small Business: Clinical Care and Health Interventions (CCHI 10) in the study of disorders related to metabolic and reproductive systems (diabetes, reproductive aging and menopause, obstetrics, neonatology, etc.). Applications are reviewed in EMS if the aims focus on improved therapeutic strategies and bio-engineering approaches for monitoring and studying these disorders. Applications are reviewed in CCHI 10 if the aims involve use of the technology or device to influence health behavior and risk.
There are shared interests between the small business panels in the Endocrine and Metabolic Systems Review Branch (EMS) and Small Business: Health Services and Systems (HSS 10) in the study of disorders related to metabolic and reproductive systems (diabetes, reproductive aging and menopause, obstetrics, neonatology, etc.). Applications are reviewed in EMS if the aims focus on improved therapeutic strategies and bio-engineering approaches for monitoring and studying these disorders. Applications are reviewed in HSS 10 if the aims focus on implementation of the approach in clinical practice or for use in clinical decision support.
