Aging, Injury, Musculoskeletal, and Rheumatologic Disorders – AIMR
The Aging, Injury, Musculoskeletal, and Rheumatologic Disorders (AIMR) study section reviews applications that characterize determinants, predictors and biomarkers of the aging process, aging-related disorders, dermatological, musculoskeletal, rheumatologic, and injury phenotypes, conditions and diseases from a population health perspective. Applications reviewed will examine a range of exposures and risk factors for these disorders and processes including but not limited to genetic, epigenetic, biological, biomedical and environmental risk factors. Studies reviewed in AIMR have a population health focus, including consideration of health equity within and across populations. Applications that focus on the pathophysiology or the underlying mechanisms of these conditions especially those that primarily use animal or other experimental models are reviewed in other study sections.
Review Dates
Topics
- Studies tracing the trajectories of biological and biomedical factors associated with aging processes, and age-related conditions, including cognitive aging and dementias in large populations
- Lifecourse studies examining how the biological determinants of aging and age-related conditions at the population level can be found in exposures and conditions from earlier in life
- Studies addressing the incidence, prevalence, progression and consequences of musculoskeletal conditions in large populations including bone development, fractures, joints, osteoarthritis and bone loss
- Studies addressing the incidence, prevalence, progression and consequences of rheumatologic conditions in large populations including rheumatoid arthritis and systemic lupus erythematosus
- Studies addressing the incidence, prevalence, progression and consequences of dermatological conditions in large populations including atopic dermatitis
- Studies addressing the incidence, prevalence, progression and consequences of injury outcomes in large populations from a biological perspective including fall injuries in older adults
- Studies examining the effects of environmental and other exposures on incidence, progression, and outcomes related to aging, dermatological, musculoskeletal, rheumatologic, and injury related conditions in large populations, especially with a focus on the health outcome rather than the exposure
- Studies of incidence, prevalence and determinants of co-morbidities and multi-morbidities in aging populations as well as populations with dermatological, musculoskeletal, rheumatologic, and injury phenotypes
- Applications may use methodologies and study designs including cohort, case-control, prospective, longitudinal, retrospective, clinical trial, cross-sectional, surveillance, genetics, epigenetics, omics (i.e. genomics, transcriptomics, proteomics, metabolomics, epigenomics, metagenomics) and assessment of gene-environment interactions
Shared Interests and Overlaps
There are shared interests in age-related conditions such as Alzheimer’s disease with Neurological, Mental and Behavioral Health (NMBH). Applications that emphasize the process of aging and how aging affects the development, progression and consequences of neurological disorders and conditions are reviewed in AIMR. Applications that primarily focus on characterizing the determinants of neurological diseases and disorders are reviewed in NMBH.
There are shared interests in aging and associated musculoskeletal dysfunctions with Aging Systems and Geriatrics Study Section (ASG). Applications that emphasize the determinants and consequences associated with aging and age-related conditions in human subpopulations are reviewed in AIMR. Applications that emphasize physiological, pathophysiological and/or mechanistic aspects of age-related conditions in humans are reviewed in ASG.
There are shared interests in cognitive aging with Human Complex Mental Function Study Section (HCMF). Applications that emphasize the process of aging in human subpopulations with an epidemiological study approach is reviewed in AIMR. Applications that emphasize mechanistic approach to cognitive aging, especially laboratory-based human studies, are reviewed in HCMF.
There are shared interests in skeletal conditions with Skeletal Biology Development and Disease Study Section (SBDD). Applications that emphasize the distribution and determinants of skeletal development and bone diseases in human subpopulations are reviewed in AIMR. Applications that emphasize basic and translational aspects of normal and abnormal skeletal development and bone diseases and investigate the pathological and normal physiology of these conditions are reviewed in SBDD.
There are shared interests in studying the genetic predisposition to disease using population-based samples with Genetics of Health and Disease (GHD). Applications that emphasize how these factors contribute to health outcomes in human subpopulations are reviewed in AIMR. Applications that emphasize discovery of genetic, genomic, epigenomic elements and molecular signatures are reviewed in GHD.
