Kidney, Endocrine, and Digestive Disorders – KEDD
The Kidney, Endocrine and Digestive Disorders (KEDD) study section reviews applications that address of the determinants, predictors and biomarkers of diseases and conditions related to the kidney, endocrine, urological, and digestive systems from a population health perspective. Applications reviewed will examine a range of exposures and risk factors for these diseases and conditions including but not limited to genetic, epigenetic, biological, biomedical and environmental risk factors. Studies are reviewed with a population health focus, including consideration of health equity within and across populations. Applications that focus on the pathophysiology or the underlying mechanisms of these diseases and disorders especially those that primarily use animal or other experimental models are reviewed in other study sections.
Review Dates
Topics
- Studies addressing the incidence, prevalence, progression and consequences of kidney diseases and conditions including chronic kidney disease, acute kidney injury and kidney transplantation in large populations
- Studies addressing the incidence, prevalence, progression and consequences of liver disorders and conditions in large populations including cirrhosis, nonalcoholic fatty liver disease and liver transplantation
- Studies addressing the incidence, prevalence, progression and consequences of endocrine and metabolic disorders and conditions in large populations including obesity, type 1 and type 2 diabetes, and hormonal disorders
- Studies addressing the incidence, prevalence, progression and consequences of digestive and nutritional disorders and conditions in large populations including inflammatory bowel disease, celiac disease, Crohn’s disease, dysbiosis of gut microbiota and malnutrition
- Studies of incidence, prevalence and determinants of co-morbidities and multi-morbidities in populations with kidney, endocrine, liver, or digestive disorders
- Studies examining the effects of environmental and other exposures on incidence, progression, and outcomes related to kidney, endocrine, urological, and digestive systems in large populations, especially with a focus on the disease or disorder outcome rather than the exposure
- Applications may use methodologies and study designs including cohort, case-control, prospective, longitudinal, retrospective, clinical trial, cross-sectional, surveillance, genetics, epigenetics, omics (i.e. genomics, transcriptomics, proteomics, metabolomics, epigenomics, metagenomics) and assessment of gene-environment interactions
Shared Interests and Overlaps
There are shared interests in the effects of obesity and diabetes during pregnancy and the perinatal period on health outcomes of both the mother and offspring with Reproductive, Perinatal, and Pediatric Health (RPPH). Applications that focus on obesity and gestational diabetes as an exposure related to pregnancy and birth outcomes at the population level may be reviewed in RPPH. Applications that focus on obesity and diabetes during pregnancy and perinatal period including gestational diabetes as a health outcome at the population level may be reviewed in KEDD.
There are shared interests in understanding diabetes and obesity with Human Studies of Diabetes and Obesity (HSDO). Applications that emphasize risk or protective factors of diabetes and obesity in human subpopulations are reviewed in KEDD. Applications that emphasize mechanisms underlying the pathophysiology of diabetes and obesity are reviewed in HSDO.
There are shared interests in health behaviors with Lifestyle and Health Behaviors (LHB). Applications that emphasize health behaviors such as diet and physical activity as risk factors for diabetes and obesity from a more biological and biomedical perspective are reviewed in KEDD. Applications that emphasize the contribution of health behaviors like diet and physical activity to diabetes and obesity from a more behavioral perspective are reviewed in LHB.
There are shared interests in studying cardiometabolic disorders that incorporate obesity, diabetes and heart disease with Cardiovascular and Respiratory Diseases (CRD). Applications that focus on the role of endocrine and metabolic causes and consequences of cardiometabolic disorders at the population level are reviewed in KEDD. Applications that focus on the role of cardiovascular causes and consequences of cardiometabolic disorders at the population level are reviewed in CRD.
There are shared interests in kidney and urological conditions with Pathobiology of Kidney Disease (PBKD) and Kidney and Urological Systems Function and Dysfunction (KUFD). Applications that emphasize the determinants, predictors and biomarkers of kidney conditions in human subpopulations are reviewed in KEDD. Applications that emphasize the pathophysiology and mechanisms underlying kidney conditions including using animal models are reviewed PBKD. Applications that emphasize the developmental mechanisms and functions underlying of kidney and urological systems in humans are reviewed in KUFD.
There are shared interests in studying the genetic predisposition to disease using population-based samples with Genetics of Health and Disease (GHD). Applications that emphasize how these factors contribute to health outcomes in human subpopulations are reviewed in KEDD. Applications that emphasize discovery of genetic, genomic, epigenomic elements and molecular signatures are reviewed in GHD.
