The Acute Neural Injury & Epilepsy (ANIE) reviews patient-oriented research (including clinical trials) investigating injury to the central nervous system, acute or chronic, resulting from traumatic brain injury (TBI), concussion, stroke, intracerebral hemorrhage (ICH), spinal cord injury (SCI), and epilepsy. Proposals studying vascular contributions to cognitive impairment and dementia (VCID) as well as small vessel cerebrovascular disease (SVD) are also reviewed. This study section reviews clinical translational and pre-clinical research that gathers data from human subjects, and vertebrate animal models including rodents and non-human primates.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Pathophysiology of TBI, concussion, stroke, SCI, epilepsy, and vascular contributions to VCID
- Clinical, translational studies of TBI, concussion, stroke, SCI, VCID and epilepsy including diagnostic, management, and outcomes
- Imaging based (PET, MRI, DTI, fMRI, and MRS), and/or electrophysiological EEG, EMG evaluation of neurological or neurobehavioral status
- Development of biomarkers (imaging, tissue, blood, CSF)
- Assessment and development of intervention strategies after stroke, TBI and SCI (including deep brain stimulation, transcranial magnetic stimulation, focused ultrasound or exercise) impacting functional recovery after injury.
Shared Interests and Overlaps
ANIE, Brain Injury and Neurovascular Pathologies (BINP) and Developmental Brain Disorders (DBD) have shared interests in CV/TBI/hypoxic/ischemic stroke. ANIE is the main study section to review clinical and human-subject based studies (also imaging-heavy proposals in this context) whereas BINP reviews those applications that emphasize the use of experimental and animal models. DBD reviews those applications focused on pediatric TBI/hypoxic/ischemia (primarily neurodevelopmental effects).
ANIE and Clinical Neuroplasticity and Neurotransmitters (CNNT) have shared interests in epilepsy and SCI - ANIE is the main study section to review clinical and human-subject based studies whereas CNNT reviews those applications that emphasize the use of experimental and animal models.
ANIE and Clinical Neuroscience and Neurodegeneration (CNN) have shared interests in VCID – while CNN reviews applications primarily focused on cognitive decline from clinical neurodegenerative diseases, ANIE reviews applications primarily focused on cerebrovascular contributions to cognitive impairment.
ANIE and Motor Function, Speech and Rehabilitation (MFSR) have shared interests in VCID CVD, SCI, and TBI. MFSR primarily reviews those applications focused on behavioral measures whereas ANIE reviews those focused on neurological mechanisms and outcomes.
ANIE and Bioengineering of Neuroscience, Vision and Low Vision Technologies (BNVT) have shared interests in Epilepsy. BNVT reviews applications focused on the localization and monitoring of neural activity/epileptic seizure foci using invasive methods: implanted electrodes and ECoG whereas ANIE evaluates their efficacy with neurological outcome measures.
ANIE and Emerging Imaging Technologies in Neuroscience (EITN) have shared interests in neuroimaging and other neural technologies. EITN reviews applications that involve the development of novel imaging tools, technologies and data analytics whereas ANIE evaluates the application of novel imaging tools and technologies in the evaluation of neurological or neurobehavioral status.
There are shared interests of ANIE with Hypertension and Microcirculation (HM) and Hemostasis and Thrombosis (HT). Applications involving stroke, microcirculation and flow related to hypertension may be assigned to HM. Applications involving coagulation factors in intracranial hemorrhage/clot formation may be reviewed in HT. Applications focused on the blood brain barrier and vascular function in the treatment of neural injury and post-stroke recovery are reviewed in ANIE.