CMIA Study Section reviews molecular, structural, biochemical, and biophysical aspects of immunology. The focus is primarily on the adaptive arm of the immune system.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- The cellular, biochemical, structural, biophysical, and extra- and intracellular molecular events of T and B lymphocytes and other cells (NKT cells, NK cells, dendritic cells and monocyte/macrophages) involved in the adaptive immune responses.
- Cell\cell interactions, cell migration, cytokine and chemokine receptors.
- Signal transduction, T and B cell receptors, costimulatory molecules, Fc high and low affinity receptors, antigen processing and presentation, T cell receptor (TCR)\major histocompatibility complex (MHC)-peptide interactions.
- Intracellular metabolism as related to immune cell function. Cytoplasmic and vesicle structure/function as it relates to immune cell function.
- Transcriptional, posttranscriptional, translational and posttranslational regulation of genes involved in lymphocyte development, differentiation, or response to environmental signals or cytokines.
- Structural, biophysical, and biochemical studies of immune molecules such as antibodies, antigens, and MHC molecules. Structure and design of antibodies and other small molecules for immunotherapy. Affinity and avidity of binding to immune molecules such as antibodies or MHC.
Shared Interests and Overlaps
There are shared interests with Cellular and Molecular Immunology Study Section B (CMIB) in basic cellular and molecular aspects of immunology. Applications focusing on areas of primary and secondary lymphoid organs, GALT, BALT, or in development and differentiation of cell types may be assigned to CMIB. Applications related to intracellular molecular processes such as signaling pathways, gene regulation, epigenetics, posttranslational modifications, as well as structure/functional studies of individual macromolecules (such as antibodies) and interactions between macromolecules (such as TCR/MHC) may be assigned to CMIA.
There are shared interests with Immunity and Host Defense Study Section (IHD) in immune responses and functions. Applications focused on the immune response to a specific pathogen(s) may be assigned to IHD. Application related to the structural, biochemical and/or biophysical aspects of the immune response may be assigned to CMIA
There are shared interests with Vaccines against Microbial Diseases (VMD) in basic immune mechanism and responses. Applications may be assigned to CMIA if there is a focus on structure/function of antibodies or of antibody engineering and biochemistry. Applications focused on the specific vaccine responses may be assigned to VMD.
There are shared interests with Molecular Genetics (MG) in the areas of gene regulation and expression. Applications that focus mainly on genetics, gene regulation, histone regulation and control, and epigenetics may go to MGA or MGB. Applications may be assigned to CMIA if the focus is on the immunological outcome of such studies.
There are shared interests with Macromolecular Structure and Function A, B, C Study Sections (MSFA, MSFB, MSFC) in mathematical modeling, computational biology and structure analyses. Applications that focus on macromolecule structure/function, bioinformatics, and computer modeling may go to MSF -A, -B, -C. Applications may be assigned to CMIA if there is a focus on the immunological outcome of such studies.