Surgery, Anesthesiology and Trauma Study Section – SAT
The Surgery, Anesthesiology, and Trauma Study Section (SAT) reviews applications examining the complementary disciplines of surgery and anesthesiology, traumatic and acute injury, and surgical critical care. Sepsis and injury studies reviewed by SAT often address the host response to such complex insults as trauma, severe infection, or surgical stress, with a general focus on metabolic, hormonal, cellular, or immune responses of the host to these various insults. SAT also reviews applications examining the basis of interventions including mechanisms of anesthesia/analgesia, wound repair, organ recovery, and cellular and immunological therapies. Topics related to anesthesiology and surgical critical care are comprehensively reviewed.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
Review Dates
Topics
- Multiorgan and systemic injury responses to surgery, trauma, burn, sepsis, hemorrhage, ischemia-reperfusion, or resuscitation, mechanisms of host response. including integrating pathways and signals
- Modeling, pathogenesis and therapeutic interventions for shock and multiple organ failure, and for hypoxic or oxidative cell/tissue injury and stress-induced cellular turnover and repair
- Skin and integument wound healing, including tissue/organ regeneration, and remodeling of damaged tissues, and novel therapeutic interventions for maintenance or restoration of tissue function.
- Mechanisms of action and pharmacology of general and local anesthetics, and pain management, including general and local anesthesia, and anesthetic side effects
- Surgical approaches to organ/tissue-specific disease, injury, or repair including minimally invasive approaches and transluminal surgery
- Genetic and epigenetic determinants of response to injury or sepsis; and genetic, epigenetic, or pharmacologic approaches for treatment
Shared Interests and Overlaps
SAT and Bioengineering, Technology and Surgical Sciences Study Section (BTSS) have shared interests in surgery. Applications related to cardiac surgery are reviewed in the BTSS. Applications of surgery related to other organs for example, lung transplantation, are typically reviewed in the SAT. However, they are reviewed in the BTSS if they have an engineering or robotic technology aspect.
SAT and Hemostasis, Thrombosis, Blood Cells and Transfusion (HTBT) have shared interests in sepsis. Applications that emphasize involving sepsis and surgery, injury, or surgical critical care will be reviewed in SAT. Applications that empathize involving sepsis and coagulation mechanisms or effects will be reviewed in HTBT.
There are shared interests with Integrative Myocardial Physiology/Pathophysiology B Study Section (MPBB) in the investigation of ischemia reperfusion injury. Grant applications that focus on multiorgan and systemic ischemia reperfusion injury that include heart, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on mechanisms of myocardial ischemia reperfusion injury should be assigned to MPPB.
There are shared interests with Neural Oxidative Metabolism and Death Study Section (NOMD) in the investigation of ischemia reperfusion injury. Grant applications that focus on multiorgan and systemic ischemia reperfusion injury that include neuro, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on molecular mechanisms underlying neural injury associated with ischemia, reperfusion injury, and traumatic brain injury may be assigned to NOMD.
There are shared interests with Kidney, Urology, and Digestive Systems Review Branch (KUDS) in the investigation of ischemia reperfusion injury and transplantation. Grant applications that focus on multiorgan and systemic ischemia reperfusion injury that includes kidney or liver, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on liver ischemia-reperfusion injury or application of transplantation to the therapy of liver diseases may be assigned to Hepatobiliary Pathophysiology Study Section (HBPP) in KUDS. Applications focusing on kidney injury and repair should be assigned to Pathobiology of Kidney Disease Study Section (PBKD) in KUDS. Applications of kidney transplantation and renal replacement therapies may be assigned to Kidney and Urological Systems Function and Dysfunction Study Section (KUFD) in KUDS.
There are shared interests with Clinical Integrative Cardiovascular and Hematological Sciences (CCHS) in the investigation of ischemia reperfusion injury. Grant applications that focus on multiorgan and systemic ischemia reperfusion injury that include heart, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on patients-oriented research on cardiovascular injury and repair, and myocardial ischemia/reperfusion injury may be assigned to CCHS.
There are shared interests with Brain Injury and Neurovascular Pathologies Study Section (BINP) in the investigation of ischemia reperfusion injury. Grant applications that focus on multiorgan and systemic ischemia reperfusion injury that include brain, and that focus on host response including hormonal, metabolic, and immune response to ischemia reperfusion injury may be assigned to SAT. Applications that focus on mechanisms of neural injury, related brain ischemia and traumatic brain injury may be assigned to BINP.
There are shared interests with Neurobiology of Pain and Itch Study Section (NPI) in the investigation of pain. Grant applications that focus on mechanisms of action and pharmacology of general and local anesthetics, and pain management, including general and local anesthesia, and anesthetic side effects may be assigned to SAT. Applications that focus on the molecular biology, anatomy, physiology, and psychophysics of pain, analgesia and somatosensory systems may be assigned to NPI.
There are shared interests with Immunobiology of Transplantation and Alloimmunity (ITA) in transplantation. Applications focusing on addressing the immune mechanisms of, and immune responses to, transplant injury, and immune modulation to improve transplantation outcomes may be reviewed in ITA. Applications proposing to study tissue and organ injury unrelated to immunology may be reviewed in SAT.
There are shared interests with Pulmonary Injury, Repair, and Remodeling (PIRR). Applications associated with acute lung injury (ALI) caused by sepsis, those focused on the mechanisms underlying the pathogenesis of ALI, and development of stem cell-based and pharmacological approaches for treatment may be reviewed in PIRR. Applications involving the study of systemic injury and responses to sepsis may be reviewed in SAT.
There are shared interests with Skin and Connective Tissue Science (SCTS) in the investigation of skin and integument wound healing and tissue regeneration. Applications that focus on biology, physiology, development and homeostasis of the skin, and skin disorders including genetic, inflammatory, hyperproliferative, pre-neoplastic, blistering, and fibrotic disorders may be assigned to SCTS. Applications that focus on tissue/organ regeneration, and remodeling of damaged tissues, and novel therapeutic interventions for maintenance or restoration of tissue function may be assigned to SAT.
