The Cancer Genetics [CG] Study Section reviews applications related to the identification and characterization of target genes involved in tumor pathogenesis. Applications in the area of genomic instability and epigenetics are also reviewed in this study section. Translational studies using mammalian and non-mammalian models, and cell lines are included.
The Cancer Genetics [CG] Study Section reviews applications related to the identification and characterization of target genes involved in tumor pathogenesis using global scale genomic and epigenomic approaches. Applications in the research area of genomic instability are also reviewed in this study section.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Oncogene discovery, genomics, and proteomics (including molecular and biochemical profiling), animal models for gene discovery, positional cloning
- Cancer genetics, including hereditary and somatic DNA alterations, allelic imbalance, and loss of heterozygosity (LOH)
- Epigenetics in cancer pathogenesis, including gene regulation, DNA methylation and histone modifications
- Functional genomics and epigenomics of cancer, including aberrant nuclear architecture and RNA-based gene regulation
- Genomic instability, including microsatellite and chromosomal instability, telomeres and telomerase regulation
- Genes that modify susceptibility to cancer including low penetrance genes identified in human and animal models
There are shared interests with Cancer Molecular Pathobiology (CAMP) on the role of epigenetics, chromatin structure and non-coding RNAs (ncRNAs) in cancer. Applications focusing on the roles of epigenetics, chromatin structures, and regulatory ncRNAs in tumorigenesis on a global scale may be assigned to CG. Applications that focus on identified targets and pathways may be assigned to CAMP.
There are shared interests with Cancer Etiology (CE) in studies of genomic instability and telomeres. Applications with focus on genetic and epigenetic aspects of genomic instability and telomeres regulation should be assigned to CG. Applications aiming to investigate genomic instability and telomeres with a focus on DNA damage and repair and environment interactions may be assigned to CE.
There are shared interests with GCAT Genomics, Computational Biology and Technology [GCAT] in applications that propose analysis and mining of “–omic” datasets, including genetic, epigenetic, gene expression, proteomic and sequencing data. Applications focusing mainly on analysis and mining of “–omic” datasets and application of bioinformatics to study genomes, transcriptomes and proteomes of tumors and cancer cell(s), including structural variation and phylogenetic analysis of tumors should be assigned to CG. Applications that propose development of new methods and technologies that may apply to any disease in addition to cancer may be assigned to GCAT.
There are shared interests with CHSA/CHSB Cancer, Heart, and Sleep Epidemiology [CHSA & CHSB] in epidemiologic research in cancer. Applications focusing on genetic and epigenetic studies which aim to identify drivers and understand molecular pathogenesis of cancer, including animal and human studies, should be assigned to CG. Applications with epidemiologic studies, using genetic and epigenetic approaches with respect to personal characteristics, place and time in human populations should be assigned to CHSA/CHSB.