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Biochemistry and Biophysics of Membranes Study Section [BBM]

The Biochemistry and Biophysics of Membranes (BBM) Study Section reviews research applications concerned with all biochemical and biophysical aspects of membrane structure and function, and with their constituent protein and lipid components. Emphasis is on the molecular details of processes that occur on or within membranes. Areas include use of biochemical and biophysical techniques to understand the structure and function of membranes and membrane-proteins.



  • Membrane architecture: lipid-protein interactions, membrane protein folding, assembly, structure, and dynamics.
  • Methods for membrane protein structure determination, including crystallization, solid state NMR and cryo-electron microscopy.
  • Biophysics of membrane fusion mechanisms, of membrane interfaces, and signaling
  • Enzyme mechanisms within membranes and interfaces: membrane-based energy transduction, membrane-bound enzymes, function of transporters, channels, receptors, glycoproteins, lipid metabolism and lipid function.
  • Computational and modeling approaches to membranes and membrane proteins.

Shared Interests and Overlaps

There are shared interests for applications involving macromolecular biophysics and structural biology with ​Macromolecular Structure and Function A (MSFA), ​Macromolecular Structure and Function B (MSFB), ​Macromolecular Structure and Function C (MSFC) and ​Macromolecular Structure and Function D (MSFD). Applications focused on structural or biophysical analyses of RNA molecules, complexes or ribozymes, protein-nucleic complexes, biophysical properties of proteins, misfolded or unstructured proteins, or post-translational modifications of proteins may be assigned to [MSFB].

There are shared interests with Membrane Biology and Protein Processing (MBPP) in membrane biology. Studies involving structural and functional analysis of membranes using biophysical and computational approaches are reviewed in Biochemistry and Biophysics of Membranes (BBM). Studies focused on the organization and interaction of proteins, carbohydrates and lipids in membrane biogenesis are reviewed in MBPP.

There are shared interests with Biophysics of Neural Systems (BPNS) in the areas of structure function and computational studies of neural membranes and associated proteins complexes and receptors.

There are shared interests with Molecular and Integrative Signal Transduction (MIST) for applications investigating structure-function relationship of G-protein coupled receptors and other transmembrane signaling complexes.