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Acute Neural Injury and Epilepsy Study Section [ANIE]

Acute Neural Injury & Epilepsy (ANIE) reviews primarily patient-oriented research (including clinical trials) investigating epilepsy and injury to the central nervous system (CNS) resulting from traumatic brain injury (TBI), concussion, spinal cord injury (SCI), ischemic stroke and intracerebral hemorrhage. It reviews proposals to study small vessel cerebrovascular Disease (CVD), particularly Vascular Contributions to Cognitive Impairment and Dementia (VCID). Applications may investigate: biomarker, imaging, electrophysiological or neuropathological approaches to diagnosis, staging, tracking or prognosis of these disorders; cognitive consequences of injury and their substrate in structural or functional systems; development of neuroprotective, therapeutic and rehabilitative strategies. Applications primarily involve patient populations although to a lesser extent transgenic and animal injury models may also used.

Rosters

Topics

  • Changes in functional domains that are consequences of epilepsy and these injuries to the CNS.
  • Studies of changes in the neural substrate and function of brain and spinal cord in response to epilepsy and injury.
  • Neurological and neurobehavioral evaluation with neuroimaging (PET, MRI, or MRS), neuropathology and electrophysiology.
  • Development of neuroprotective, therapeutic and rehabilitative strategies, including: evaluation of neural prostheses, electrical and magnetic stimulation (including deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS)), behavioral and pharmacological interventions and physical therapy.

Shared Interests and Overlaps

ANIE, Brain Injury and Neurovascular Pathologies (BINP) and Developmental Brain Disorders (DBD) have shared interests in CVD\TBI\hypoxic/ischemic stroke. ANIE is the main study section to review clinical and human-subject based studies (also imaging-heavy proposals in this context) vs BINP reviews those applications focused on the use of experimental and animal models vs DBD reviews those applications focused on pediatric TBI/hypoxic/ischemia (primarily neurodevelopmental effects).

ANIE and Clinical Neuroplasticity and Neurotransmitters (CNNT) have shared interests in epilepsy, SCI - ANIE is the main study section to review clinical and human-subject based studies whereas CNNT reviews those applications focused on the use of experimental and animal models.

ANIE and Clinical Neuroscience and Neurodegeneration (CNN) have shared interest in VCID - CNN reviews primarily cognitive decline from clinical neurodegenerative diseases vs. cerebrovascular contributions to cognitive impairment ANIE. While ANIE is the primary site for review of TBI applications, CNN does have some shared interest.

ANIE and Motor Function, Speech and Rehabilitation (MFSR) have shared interest in VCID CVD, SCI, TBI. MFSR primarily reviews those applications focused on behavioral measures vs ANIE reviews those focused on neurological outcome measures.

ANIE, Neuroscience and Ophthalmic Imaging Technologies (NOIT) and Bioengineering of Neuroscience, Vision and Low Vision Technologies (BNVT) have shared interests in CVD, Epilepsy, SCI TBI. NOIT and BNVT review applications focused on the development/validation of diagnostic/therapeutic model or tools in these diseases and disorder vs. evaluating their efficacy with neurological outcome measures.

ANIE vs Medical Imaging (MEDI) have shared interests in CVD, Epilepsy, SCI TBI. MEDI reviews applications focused on the development/validation of imaging techniques for diagnosis or treatment vs ANIE reviews applications focused on evaluating their efficacy with neurological outcome measures.

There are shared interests of ANIE with Hypertension and Microcirculation (HM) and Hemostasis and Thrombosis (HT). Applications involving stroke, microcirculation and flow related to hypertension may be assigned to HM. Applications involving coagulation factors in intracranial hemorrhage/clot formation may be reviewed in HT. ​