The Genetic Variation and Evolution [GVE] Study Section reviews grant applications related to the origin, distribution, maintenance, and evolutionary consequences of genetic variation to provide for the expansion of fundamental knowledge about living Systems. Understanding genetic variation and evolution is central to modern approaches to biomedicine, epidemiology, health, and disease. Studies make use of mathematical models, computer simulations, viruses, microbes (prokaryotic and eukaryotic), yeast, plants, and animals, including natural populations, laboratory model systems, and humans.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Applications of evolutionary principles to: biomedicine, epidemiology, health, and disease; including host-pathogen interactions, genetics of virulence or resistance, co-evolutionary dynamics, and population structure.
- Mechanisms of evolution: selection, adaptation, mutation, recombination, gene/genome duplication, transposition, chromosomal evolution, and speciation;
- Genotype- phenotype mapping: genetics of complex traits in whole organisms, QTL mapping, association mapping, disease gene mapping, evolution of development (evo-devo), evolution of proteins and biochemical pathways/networks, genotype-environment interactions, evolvability, and heritability; role of genetic variation in gene regulation;
- Population genetics: theory, experimental approaches, and application to large genomic datasets;
- Molecular evolution from genes to genomes: phylogenetics, comparative genomics, bioinformatics, computational biology, modeling, and systems biology.
Shared Interests and Overlaps
There are shared interests with Genomics Computational Biology and Technology (GCAT) in studies of genetic variation in humans and model organisms. Applications proposing new computational methods as applied to genetic variation may be reviewed in GCAT. Applications with an evolutionary focus that use existing computational methods, or applications to develop new methods for evolutionary theory, may be reviewed in GVE.
There are shared interests with Genetics of Health and Disease (GHD). Applications that use existing evolutionary principles for gene and genetic variant discovery in diseases may be reviewed in GHD. Applications that focus on revealing evolutionary principles for the generation of genetic variation in diseases may be reviewed in GVE.
There are shared interests with Prokaryotic Cell and Molecular Biology (PCMB). Applications using existing evolutionary principles to study bacterial community, cell and molecular processes may be reviewed in PCMB. Applications investigating the evolution and generation of genetic variation using bacteria may be reviewed in GVE.
There are shared interests with IDM study sections, HIBP, PTHE, VIRA and VIRB, in the area of pathogen-host interactions. Applications that focus on genetic factors involved in the molecular mechanisms of such interactions may be reviewed in the appropriate IDM study section. Applications that focus on such interactions as a coevolution process using genomic, genetic or computational methods may be reviewed in GVE.