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IRG Summary

This IRG will review applications that involve a variety of disciplines including biochemistry, biophysics, chemistry, and genetics, and use a variety of techniques including microscopy, genomics, proteomics and computational techniques, with the primary goal of better understanding cell functions. In addition, the CB IRG includes the Biology of Visual System (BVS) study section which reviews applications on basic mechanisms of the cell, molecular and developmental biology of the eye.

Study Sections


  • Topics to be covered include cell growth, proliferation, and cell cycle control; nuclear architecture and transport; RNA trafficking and localization; post-translational modifications, protein processing, glycosylation and folding; membrane structure and function; lipid traffic and metabolism; cell asymmetry and polarity;
  • ion transport and regulation, channels, transporters and junctions; organelle biogenesis, function, dynamics and protein translocation; the secretory pathway, endocytosis, exocytosis and phagocytosis; degradative processes; cell adhesion, junctions and cell: cell fusion; extracellular matrix and ECM receptors;
  • signaling mechanisms and networks; integrative cell physiology including circadian clocks, stress and oxidative damage response; motors, filaments and cargoes; cell locomotion; mitosis and meiosis; programmed cell death and apoptosis;
  • multi-cellular interactions and development including higher order complexity in tissues; cell differentiation and oncogenic transformation; and the development of new methodologies including advances in imaging and biosensors.