The Neurodifferentiation, Plasticity, Regeneration and Rhythmicity (NDPR) Study Section reviews applications focused on differentiation, plasticity, aging, and regeneration of neuronal connectivity as well as the effects of rhythmicity on these processes. Emphasis is on fundamental cellular and molecular mechanisms underlying normal development and aging, as well as recovery from injury, disease, and pathological insults.
The List of Reviewers lists all present, whether standing members or temporary, to provide the full scope of expertise present on that date. Lists are posted 30 days before the meeting and are tentative, pending any last minute changes.
The membership panel is a list of chartered members only.
- Mechanisms controlling cell motility, directional migration, and growth cone extension
- Axonal outgrowth, fasciculation, branching, and guidance; cell polarity; dendrites and dendritic spines; selection of synaptic partners, including formation of topographic and laminar-specific projections
- Synapse formation and plasticity; initial formation and maturation of pre- and postsynaptic elements; factors regulating the elaboration and retraction of arbors and processes, including neurotrophins, cytokines, cell adhesion molecules, and physiological activity; synaptic changes in response to activity, the physiological environment, such as hormonal changes, and the external environment, including light and temperature cycles.
- Synaptic plasticity and biological rhythms: neurobiology of circadian and other rhythms in activity; synchronized neuronal oscillations involved in CNS function
- Regeneration of connections; factors that promote or direct axon or dendritic sprouting, axon or dendritic re-growth, re-formation of dendritic spines, and re-establishment of synaptic connections following injury; factors that inhibit these processes; development of cellular and molecular tools and strategies to overcome inhibitory factors and to promote regeneration
Shared Interests and Overlaps
Neurogenesis and Cell Fate (NCF): There is shared interest in neurodevelopment. Applications focused on early determination in the nervous system as well as neural stem cell biology may be reviewed in NCF whereas applications focused on later differentiation in the nervous system and related aspects of plasticity and regeneration may be reviewed in NDPR.
Cellular and Molecular Biology of Glia (CMBG): There is shared interest in the function of glia, particularly in the area of glia-neuron interactions. When the focus is on the neuronal function and how it is influenced by glia, the application may be reviewed by NDPR.
Synapses, Cytoskeleton and Trafficking (SYN): There are many shared interests. SYN has a stronger focus on synaptic function, including cytoskeletal dynamics and trafficking, while NDPR has a greater interest in development, including synaptogenesis and related aspects of synaptic plasticity during maturation and in the context of regeneration.
Development-1 (Dev1) and Development-2 [DEV2]: There is shared interest in development. DEV1 and DEV2 review topics related to those considered in NDPR but with a focus on structures outside of the nervous system.
Cellular Mechanisms in Aging and Development (CMAD): There are shared interests in development and aging with CMAD. When the focus is on mechanisms and events within the nervous system, the applications may be reviewed by NDPR. When the focus is on broader mechanisms involving the whole organism or structures primarily outside the nervous system, application may be reviewed by CMAD
Biology of the Visual System (BVS): NDPR and BVS share an interest in retinal development and regeneration. When the focus is on basic mechanisms of axon outgrowth, morphological differentiation, synaptogenesis, and regeneration, applications may be reviewed by NDPR. When functional organization of the retina is a major focus, applications may be reviewed by BVS.
Developmental Brain Disorders (DBD): There is shared interest in development. Applications with focus on human development in the context of diseases may be reviewed in DBD whereas applications involving basic molecular and cellular mechanisms in a wide variety of scientific models may be reviewed in NDPR.
Clinical Neuroplasticity and Neurotransmitters (CNNT): There is shared interest in neuroplasticity and regeneration. Applications with a greater clinical and translational focus may be reviewed in CNNT while applications centered predominantly on basic cellular and molecular mechanisms of synaptogenesis, plasticity, and regeneration may be reviewed in NDPR.
Diseases and Pathophysiology of the Visual System (DPVS): There is shared interest in the retina and optic nerve. Application focused on cellular and molecular mechanisms underlying axon outgrowth, synaptogenesis, and regeneration may be reviewed by NDPR. More translational and clinical-oriented studies may be reviewed by DPVS.
Neurobiology of Learning and Memory Study Section [LAM]: There is shared interest in synaptic plasticity and development. Applications with a focus on systems neuroscience and functional circuitry may be reviewed in LAM while applications involving primarily cellular and molecular mechanisms may be reviewed in NDPR.
Neuroendocrinology, Neuroimmunology, Rhythms and Sleep Study Section [NNRS]: There is shared interest in circadian rhythms and other rhythmic systems. When the focus is on cellular or molecular mechanisms, particularly at the sub-cellular level, applications may be reviewed by NDPR. When there is a more systems level focus, applications may be reviewed by NNRS
Molecular Neurogenetics (MNG): There is a shared interest in the mechanisms and function of molecular genetics, including cellular genomics, transcriptional and translational regulation, and epigenetics. When the focus is on the molecular mechanisms of a genetic process, the application may be reviewed by MNG. In contrast, when the focus is on the function or involvement of molecular genetics in differentiation, plasticity, or regeneration of the nervous system, the application may be reviewed by NDPR.